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Mir23b Gene Detail
Summary
  • Symbol
    Mir23b
  • Name
    microRNA 23b
  • Synonyms
    Mirn23b, mmu-mir-23b
Location &
Maps
more
  • Sequence Map
    Chr13:63448298-63448371 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 32.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    35 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676898
miRNA gene Chr13:63448298-63448371 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008077
miRNA gene Chr13:63260577-63260650 (+)
A/J MGP_AJ_G0008067
miRNA gene Chr13:60958743-60958816 (+)
AKR/J MGP_AKRJ_G0008046
miRNA gene Chr13:63000878-63000951 (+)
BALB/cJ MGP_BALBcJ_G0008050
miRNA gene Chr13:61387175-61387248 (+)
C3H/HeJ MGP_C3HHeJ_G0007993
miRNA gene Chr13:62533093-62533166 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008235
miRNA gene Chr13:65321327-65321400 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007338
miRNA gene Chr13:58632886-58632959 (+)
CAST/EiJ MGP_CASTEiJ_G0007876
miRNA gene Chr13:62536081-62536154 (+)
CBA/J MGP_CBAJ_G0007962
miRNA gene Chr13:67842048-67842121 (+)
DBA/2J MGP_DBA2J_G0007996
miRNA gene Chr13:60801667-60801740 (+)
FVB/NJ MGP_FVBNJ_G0008018
miRNA gene Chr13:59919000-59919073 (+)
LP/J MGP_LPJ_G0008079
miRNA gene Chr13:63537387-63537460 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007988
miRNA gene Chr13:66815257-66815330 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008233
miRNA gene Chr13:62305516-62305589 (+)
PWK/PhJ MGP_PWKPhJ_G0007797
miRNA gene Chr13:60359981-60360054 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007692
miRNA gene Chr13:60460827-60460900 (+)
WSB/EiJ MGP_WSBEiJ_G0007948
miRNA gene Chr13:62795727-62795800 (+)



Homology
more
  • Human Ortholog
    MIR23B, microRNA 23b
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR23B, microRNA 23b
  • Synonyms
    hsa-mir-23b, mir-23b, MIRN23B, miRNA23B
  • Links
    NCBI Gene ID: 407011

  • Chr Location
    chr9:95085208-95085304 (+)  GRCh38

Human Diseases
more
  • Diseases
    2 with human MIR23B associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Mir23b
  • Find Mice (IMSR)
Mice homozygous for a targeted deletion are viable with no observed pathologies.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 387217 NCBI Gene Model | MGI Sequence Detail 74 C57BL/6J ±  kb
transcript NR_029530 RefSeq | MGI Sequence Detail 74 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 7
    Primer pair 2
    Other 5
Other Database
Links
less
miRBase MI0000141
References
more
  • Summaries
    All 42
    Developmental Gene Expression 14
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:342842 Su D, et al., Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development. J Biol Chem. 2023 Nov;299(11):105324

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory