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Mir200b Gene Detail
Summary
  • Symbol
    Mir200b
  • Name
    microRNA 200b
  • Synonyms
    Mirn200b, mmu-mir-200b
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676875
    NCBI Gene: 387243
  • Member of
    Mirc4 cluster
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr4:156055681-156055750 bp, - strand
  • From miRBase annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      70 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 87.96 cM
  • Mapping Data
    1 experiment
Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from multigenic genotypes
    1 phenotype reference
Mice homozygous for knock-out alleles for Mir429 and Mir200b exhibit reduced female ferility due to reduced ovulation and impaired luteinizing hormone production.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 387243 NCBI Gene Model | MGI Sequence Detail 70 C57BL/6J ±  kb
transcript NR_029587 RefSeq | MGI Sequence Detail 70 C57BL/6  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    51 from dbSNP Build 142
Molecular
Reagents
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  • All nucleic 3
    Primer pair 1
    Other 2
Other Database
Links
less
References
more
  • Summaries
    All 34
    Developmental Gene Expression 14
    Gene Ontology 7
    Phenotypes 1
  • Earliest
    J:84908 Lagos-Quintana M, et al., New microRNAs from mouse and human. RNA. 2003 Feb;9(2):175-9
  • Latest
    J:231786 Garaffo G, et al., The Dlx5 and Foxg1 transcription factors, linked via miRNA-9 and -200, are required for the development of the olfactory and GnRH system. Mol Cell Neurosci. 2015 Sep;68:103-19

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/07/2017
MGI 6.11
The Jackson Laboratory