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Mir18 Gene Detail
Summary
  • Symbol
    Mir18
  • Name
    microRNA 18
  • Synonyms
    Mirn18, mmu-mir-18, mmu-mir-18a
Location &
Maps
more
  • Sequence Map
    Chr14:115281283-115281378 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 59.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    83 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676844
 miRNA gene Chr14:115281283-115281378 (+)
129S1/SvImJ ENSMUSG00200024704
 miRNA gene Chr14:104178213-104178308 (+)
A/J ENSMUSG00195032087
 miRNA gene Chr14:103932841-103932936 (+)
AKR/J ENSMUSG00220007785
 miRNA gene Chr14:103710808-103710903 (+)
BALB/cJ ENSMUSG00180029060
 miRNA gene Chr14:103425041-103425136 (+)
C3H/HeJ ENSMUSG00175005956
 miRNA gene Chr14:105360807-105360902 (+)
C57BL/6NJ ENSMUSG00215025472
 miRNA gene Chr14:103546526-103546621 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007397
 miRNA gene Chr14:104418047-104418142 (+)
CAST/EiJ ENSTCUG00005007147
 miRNA gene Chr14:105045178-105045273 (+)
CBA/J ENSMUSG00210027303
 miRNA gene Chr14:104329495-104329590 (+)
DBA/2J ENSMUSG00185021640
 miRNA gene Chr14:109485814-109485909 (+)
FVB/NJ ENSMUSG00205007700
 miRNA gene Chr14:103040673-103040768 (+)
JF1/MsJ ENSUMUG00000012906
 miRNA gene Chr14:120537442-120537537 (+)
LP/J ENSMUSG00230001893
 miRNA gene Chr14:121479607-121479702 (+)
NOD/ShiLtJ ENSMUSG00190027575
 miRNA gene Chr14:104119871-104119966 (+)
NZO/HlLtJ ENSMUSG00225021488
 miRNA gene Chr14:111482331-111482426 (+)
PWK/PhJ ENSLUMG00010029207
 miRNA gene Chr14:103389973-103390068 (+)
SPRET/EiJ ENSMSPG00010012327
 miRNA gene Chr14:107571758-107571853 (+)
WSB/EiJ ENSIUOG00005031275
 miRNA gene Chr14:103310670-103310765 (+)



Homology
more
  • Human Ortholog
    MIR18A, microRNA 18a
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR18A, microRNA 18a
  • Synonyms
    C13orf25, hsa-mir-18, hsa-mir-18a, miR-18, MIR18, mir-18a, MIRH1, MIRHG1, MIRN18, MIRN18A, miRNA18A
  • Links
    NCBI Gene ID: 406953

  • Chr Location
    chr13:91350751-91350821 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Mir18
  • Find Mice (IMSR)
    2 strains or lines available
Mice homozygous for a knock-out allele are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    58
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    665
  • Tissues
    50
  • Literature Summary
    19
Sequences &
Gene Models
less
  • All Sequences
    25
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 387135 NCBI Gene Model | MGI Sequence Detail 96 C57BL/6J ±  kb
transcript NR_029736 RefSeq | MGI Sequence Detail 96 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 6
    Primer pair 5
    Other 1
Other Database
Links
less
miRBase MI0000567
References
more
  • Summaries
    All 50
    Developmental Gene Expression 19
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:67314 Roix J, et al., Molecular and functional mapping of the piebald deletion complex on mouse chromosome 14. Genetics. 2001 Feb;157(2):803-15
  • Latest
    J:357455 Wang T, et al., miR-181c-5p suppresses neuronal pyroptosis via NLRP1 in Alzheimer's disease. Behav Brain Res. 2023 Jun 5;447:114387
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory