About   Help   FAQ
Mir146
Gene Detail
 Symbol
Name
ID
Mir146
microRNA 146
MGI:2676831
BioType Conflict
Synonyms miR-146a, Mirn146, mmu-mir-146, mmu-mir-146a
Feature Type miRNA gene
Genetic Map
Chromosome 11
25.68 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:43374397-43374461 bp, - strand
From miRBase annotation of GRCm38

  65 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Mir146
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
 
Mice homozygous for a knock-out allele exhibit increased sensitivity to LPS and develop a lympho- and myeloproliferative syndrome.
 
Human Diseases Modeled Using Mouse Mir146 (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(3)
Interactions
Mir146 interacts with 6574 markers (0610009O20Rik, 0610010F05Rik, 0610030E20Rik, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process cellular response to estrogen stimulus, cellular response to lipopolysaccharide, ...
Expression
Literature Summary: (6 records)
Data Summary: Results (6)    Tissues (4)    Images (1)
Theiler Stages: 15, 17, 19, 28
Assay TypeResults
Northern blot 3
RT-PCR 3
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(3) Primer pair(1) Other(2)
Other database
links
Ensembl Gene ModelENSMUSG00000065601 (Evidence)
Entrez Gene387164 (Evidence)
miRBaseMI0000170
International Mouse Knockout Project StatusMir146
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 387164 NCBI Gene Model | MGI Sequence Detail 65 C57BL/6J ±  kb
transcript NR_029558 RefSeq | MGI Sequence Detail 65 C57BL/6 

For the selected sequences
All sequences(5) RefSeq(1)
Polymorphisms SNPs within 2kb(29 from dbSNP Build 137)
References (Earliest) J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
(Latest) J:207804 Zhao JL, et al., MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice. Elife. 2013;2:e00537
All references(36)
Disease annotation references (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory