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Nrde2 Gene Detail
Summary
  • Symbol
    Nrde2
  • Name
    nrde-2 necessary for RNA interference, domain containing
  • Synonyms
    6720454P05Rik, BC002230
  • Feature Type
    protein coding gene
  • IDs
    MGI:2670969
    NCBI Gene: 217827
Location & Maps
more
  • Sequence Map
    Chr12:100125452-100159653 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      34202 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    NRDE2, NRDE-2, necessary for RNA interference, domain containing
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NRDE2, NRDE-2, necessary for RNA interference, domain containing
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C14orf102
  • Links
    NCBI Gene ID: 55051
    neXtProt AC: NX_Q9H7Z3

  • Chr Location
    14q32.11; chr14:90278054-90332137 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 41213
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: NRDE2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    16
  • Chemically induced (other)
    1
  • Gene trapped
    11
  • Targeted
    4
  • Genomic Mutations
    1 involving Nrde2
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021179 Ensembl Gene Model | MGI Sequence Detail 34202 C57BL/6J ±  kb
transcript ENSMUST00000021596 Ensembl | MGI Sequence Detail 3723 Not Applicable  
polypeptide ENSMUSP00000021596 Ensembl | MGI Sequence Detail 1172 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    141 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR013633 siRNA-mediated silencing protein NRDE-2
    IPR011990 Tetratricopeptide-like helical domain
Molecular
Reagents
less
  • All nucleic 79
    cDNA 79

    Microarray probesets 2
Other
Accession IDs
less
MGI:2443747
References
more
  • Summaries
    All 26
    Phenotypes 10
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory