Nrde2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nrde2
nrde-2 necessary for RNA interference, domain containing
MGI:2670969

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nrde2^{em1(IMPC)Ccpcz}/Nrde2⁺ C57BL/6NCrl-Nrde2^{em1(IMPC)Ccpcz}/Ccpcz	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	enlarged heart	J:211773
	enlarged kidney	J:211773
	fused cornea and lens	J:211773
	increased effector memory CD8-positive, alpha-beta T cell number	J:211773
	increased effector memory T-helper cell number	J:211773
Nrde2^{em1(IMPC)Ccpcz}/Nrde2^{em1(IMPC)Ccpcz} C57BL/6NCrl-Nrde2^{em1(IMPC)Ccpcz}/Ccpcz	preweaning lethality, complete penetrance	J:211773
Nrde2^{tm2a(KOMP)Wtsi}/Nrde2⁺ C57BL/6N-Nrde2^{tm2a(KOMP)Wtsi}/Wtsi	increased bone mineral content	J:211773
Nrde2^{tm2a(KOMP)Wtsi}/Nrde2^{tm2a(KOMP)Wtsi} C57BL/6N-Nrde2^{tm2a(KOMP)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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