About   Help   FAQ
Tspoap1 Gene Detail
Summary
  • Symbol
    Tspoap1
  • Name
    TSPO associated protein 1
  • Synonyms
    Bzrap1, mKIAA0612, peripheral
  • Feature Type
    protein coding gene
  • IDs
    MGI:2450877
    NCBI Gene: 207777
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:87760541-87785928 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 52.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    217 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2450877
protein coding gene Chr11:87758194-87785928 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018911
protein coding gene Chr11:89392775-89418614 (+)
A/J MGP_AJ_G0018878
protein coding gene Chr11:85946243-85972146 (+)
AKR/J MGP_AKRJ_G0018848
protein coding gene Chr11:88515809-88546266 (+)
BALB/cJ MGP_BALBcJ_G0018851
protein coding gene Chr11:86347937-86373306 (+)
C3H/HeJ MGP_C3HHeJ_G0018665
protein coding gene Chr11:88560572-88586772 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019303
protein coding gene Chr11:92108335-92135197 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016936
protein coding gene Chr11:82974008-82999710 (+)
CAST/EiJ MGP_CASTEiJ_G0018220
protein coding gene Chr11:89252494-89279605 (+)
CBA/J MGP_CBAJ_G0018636
protein coding gene Chr11:95977947-96003481 (+)
DBA/2J MGP_DBA2J_G0018744
protein coding gene Chr11:85500419-85526049 (+)
FVB/NJ MGP_FVBNJ_G0018733
protein coding gene Chr11:85006528-85031885 (+)
LP/J MGP_LPJ_G0018814
protein coding gene Chr11:89884332-89910937 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018760
protein coding gene Chr11:96017638-96042991 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019343
protein coding gene Chr11:88758439-88783785 (+)
PWK/PhJ MGP_PWKPhJ_G0017990
protein coding gene Chr11:86349703-86375156 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017783
protein coding gene Chr11:88317535-88342841 (+)
WSB/EiJ MGP_WSBEiJ_G0018271
protein coding gene Chr11:88649491-88676505 (+)



Homology
more
  • Human Ortholog
    TSPOAP1, TSPO associated protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TSPOAP1, TSPO associated protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BZRAP1, PBR-IP, PRAX1, PRAX-1, RIMBP1, RIM-BP1
  • Links
    NCBI Gene ID: 9256
    neXtProt AC: NX_O95153
    UniProt: O95153

  • Chr Location
    17q22; chr17:58301227-58329030 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    14 phenotype references
Homozygous double-KO with Rimbp2tm1.2Geno does not exacerbate the phenotype of the latter single KO.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034156 Ensembl Gene Model | MGI Sequence Detail 25388 C57BL/6J ±  kb
transcript ENSMUST00000039627 Ensembl | MGI Sequence Detail 7616 Not Applicable  
polypeptide ENSMUSP00000048063 Ensembl | MGI Sequence Detail 1846 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 56
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 14
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:238503 Grauel MK, et al., RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11615-11620

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/26/2019
MGI 6.14
The Jackson Laboratory