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Cyp3a44
Gene Detail
Symbol

Name
ID
Cyp3a44
cytochrome P450, family 3, subfamily a, polypeptide 44
MGI:2449818
Feature Type
protein coding gene
Genetic Map
Chromosome 5
85.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:145773983-145805874 bp, - strand
From VEGA annotation of GRCm38

  31892 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133568  Vertebrate Homology Class
1 human; 5 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque

HCOP human homology predictions: CYP3A5
Protein SuperFamily: trichodiene oxygenase
Gene Tree: Cyp3a44

Human
homologs
CYP3A5, cytochrome P450, family 3, subfamily A, polypeptide 5
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1577
neXtProt AC: NX_P20815

Human Synonyms: CP35, CYPIIIA5, P450PCN3, PCN3

Human Chr (Location): 7q21.1; chr7:99648189-99680026 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CYP3A5

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Genomic Mutations involving Cyp3a44 (2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Cyp3a44 interacts with 74 markers (Mir10a, Mir15b, Mir20a, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(2)
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(12) Genomic(10) cDNA(2)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000025126 (Evidence)
Ensembl Gene Model ENSMUSG00000054417 (Evidence)
Entrez Gene 337924 (Evidence)
UniGene 425301
DoTS DT.101407142
Consensus CDS Project CCDS19864.1
International Mouse Phenotyping Consortium Status Cyp3a44
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025126 VEGA Gene Model | MGI Sequence Detail 31892 C57BL/6J ±  kb
transcript OTTMUST00000061808 VEGA | MGI Sequence Detail 1962 Not Applicable 
polypeptide OTTMUSP00000030400 VEGA | MGI Sequence Detail 504 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(3) UniProt(1)
Polymorphisms
SNPs within 2kb(132 from dbSNP Build 137)    SNPs within 2kb including multiple locations(154)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR008072 Cytochrome P450, E-class, CYP3A
InterPro IPR002402 Cytochrome P450, E-class, group II
References
(Earliest) J:81656 Sakuma T, et al., Regulation of the expression of two female-predominant CYP3A mRNAs (CYP3A41 and CYP3A44) in mouse liver by sex and growth hormones. Arch Biochem Biophys. 2002 Aug 15;404(2):234-42
(Latest) J:85786 Zaphiropoulos PG, A map of the mouse Cyp3a locus. DNA Seq. 2003 Jun;14(3):155-62
All references(18)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory