About   Help   FAQ
Atcay
Gene Detail
Symbol

Name
ID
Atcay
ataxia, cerebellar, Cayman type homolog (human)
MGI:2448730
Synonyms
3322401A10Rik, BNIP-H, ji
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(10)
Sequence Map
Chr10:81204508-81230833 bp, - strand
From VEGA annotation of GRCm38

  26326 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13206  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Atcay

Human
homologs
Human Homolog ATCAY, ataxia, cerebellar, Cayman type
NCBI Gene ID 85300
neXtProt AC  NX_Q86WG3
Human Synonyms  BNIP-H, CLAC
Human Chr (Location)  19p13.3; chr19:3880620-3928082 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ATCAY
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Chemically induced (ENU)(1) Gene trapped(1) Spontaneous(4) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mutants homozygous for a severe allele show progressive impaired coordination and seizures beginning by 10-16 days of age and die by 4 weeks of age. Homozygotes for milder alleles have abnormal gait, slightly diminished body size and reduced male fertility.
 
Human Diseases Modeled Using Mouse Atcay (1)    Alleles Annotated to Human Diseases(3)   
Interactions
Atcay interacts with 274 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process apoptotic process, mitochondrion distribution, ...
Component axon, cell junction, ...
Function kinesin binding, WW domain binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (203)    Tissues (28)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 194
Northern blot 9
cDNA source data(48)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) cDNA(49)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000030319 (Evidence)
Ensembl Gene ModelENSMUSG00000034958 (Evidence)
Entrez Gene16467 (Evidence)
UniGene127681
DFCITC1574224
DoTSDT.91321000
NIA Mouse Gene IndexU032038
Consensus CDS ProjectCCDS24047.1
International Mouse Knockout Project StatusAtcay
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030319 VEGA Gene Model | MGI Sequence Detail 26326 C57BL/6J ±  kb
transcript OTTMUST00000075100 VEGA | MGI Sequence Detail 3736 Not Applicable 
polypeptide OTTMUSP00000039302 VEGA | MGI Sequence Detail 372 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(65 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR022181 Bcl2-/adenovirus E1B 19kDa-interacting protein 2
InterPro IPR001251 CRAL-TRIO domain
Protein Ontology PR:000004395 caytaxin
References
(Earliest) J:300 Snell GD, Linkage of jittery and waltzing in the mouse. J Hered. 1945;36:279-80
(Latest) J:212116 Luna-Cancalon K, et al., Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcay(ji-hes) mice. Neurobiol Dis. 2014 Jul;67:140-8
All references(48)
Disease annotation references (2)
Other
accession IDs
MGD-MRK-10693, MGD-MRK-11529, MGI:2143893, MGI:2442176, MGI:96640

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/18/2014
MGI 5.20
The Jackson Laboratory