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Hist4h4 Gene Detail
Summary
  • Symbol
    Hist4h4
  • Name
    histone cluster 4, H4
  • Synonyms
    B130044J01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448443
    NCBI Gene: 320332
  • Gene Overview
    MyGene.info: HIST4H4
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr6:136803993-136804431 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 66.72 cM, cytoband G1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448443
protein coding gene Chr6:136801553-136804431 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0031868
protein coding gene Chr6:145138166-145142417 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031088
protein coding gene Chr6:150530468-150536100 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0031196
protein coding gene Chr6:133437412-133441549 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0031236
protein coding gene Chr6:154420238-154426596 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031900
protein coding gene Chr6:139551928-139554189 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0030047
protein coding gene Chr6:137807261-137811390 (-)
WSB/EiJ MGP_WSBEiJ_G0030589
protein coding gene Chr6:140178641-140180864 (-)



Homology
more
  • Human Ortholog
    HIST1H4B, histone cluster 1 H4 family member b
  • Vertebrate Orthologs
    8
  • Human Ortholog
    HIST1H4B, histone cluster 1 H4 family member b
    Orthology source: HomoloGene
  • Synonyms
    H4FI, H4/I
  • Links
    NCBI Gene ID: 8366
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    6p22.2; chr6:26026896-26027252 (-)  GRCh38.p7

  • Human Ortholog
    HIST4H4, histone cluster 4 H4
    Orthology source: HGNC
  • Synonyms
    H4/p
  • Links
    NCBI Gene ID: 121504
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    12p12.3; chr12:14770720-14771131 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 320332 NCBI Gene Model | MGI Sequence Detail 439 C57BL/6J ±  kb
transcript NM_175652 RefSeq | MGI Sequence Detail 439 C57BL/6  
polypeptide NP_783583 RefSeq | MGI Sequence Detail 103 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 5
    Genomic 1
    cDNA 3
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:2443829
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:256001 Jung EM, et al., Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior. Nat Neurosci. 2017 Dec;20(12):1694-1707

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory