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Hist1h4a Gene Detail
Summary
  • Symbol
    Hist1h4a
  • Name
    histone cluster 1, H4a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448419
    NCBI Gene: 326619
  • Member of
    Hist1 cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr13:23760795-23761249 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 9.91 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448419
protein coding gene Chr13:23760692-23761249 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020365
protein coding gene Chr13:21204594-21205134 (-)
A/J MGP_AJ_G0020314
protein coding gene Chr13:20813843-20814383 (-)
AKR/J MGP_AKRJ_G0020294
protein coding gene Chr13:21067364-21068031 (-)
BALB/cJ MGP_BALBcJ_G0020312
protein coding gene Chr13:20807792-20810854 (-)
C3H/HeJ MGP_C3HHeJ_G0020116
protein coding gene Chr13:21139375-21140608 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020749
protein coding gene Chr13:21984718-21985256 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018337
protein coding gene Chr13:19587539-19588079 (-)
CAST/EiJ MGP_CASTEiJ_G0019635
protein coding gene Chr13:20822363-20822903 (-)
CBA/J MGP_CBAJ_G0020070
protein coding gene Chr13:22838927-22842104 (-)
DBA/2J MGP_DBA2J_G0020196
protein coding gene Chr13:20341921-20342461 (-)
FVB/NJ MGP_FVBNJ_G0020180
protein coding gene Chr13:19992495-19994122 (-)
LP/J MGP_LPJ_G0020269
protein coding gene Chr13:21512906-21514419 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020207
protein coding gene Chr13:23134714-23135254 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020791
protein coding gene Chr13:20920170-20920710 (-)
PWK/PhJ MGP_PWKPhJ_G0019387
protein coding gene Chr13:20368858-20374127 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019204
protein coding gene Chr13:19724274-19726277 (-)
WSB/EiJ MGP_WSBEiJ_G0019693
protein coding gene Chr13:21057397-21057935 (-)



Homology
more
  • Human Ortholog
    HIST2H4B, histone cluster 2 H4 family member b
  • Vertebrate Orthologs
    9
  • Human Ortholog
    HIST2H4B, histone cluster 2 H4 family member b
    Orthology source: HomoloGene
  • Synonyms
    H4/o
  • Links
    NCBI Gene ID: 554313
    neXtProt AC: NX_P62805
    UniProt: P62805

  • Chr Location
    1q21.2; chr1:149860764-149861159 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Hist1h4a
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 326619 NCBI Gene Model | MGI Sequence Detail 455 C57BL/6J ±  kb
transcript NM_178192 RefSeq | MGI Sequence Detail 455 C57BL/6  
polypeptide NP_835499 RefSeq | MGI Sequence Detail 103 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 6
    Genomic 1
    cDNA 4
    Primer pair 1
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:187380 Dey A, et al., Loss of the tumor suppressor BAP1 causes myeloid transformation. Science. 2012 Sep 21;337(6101):1541-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory