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Prss50 Gene Detail
Summary
  • Symbol
    Prss50
  • Name
    protease, serine 50
  • Synonyms
    Tsp50
  • Feature Type
    protein coding gene
  • IDs
    MGI:2447303
    NCBI Gene: 235631
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr9:110857967-110864629 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6663 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 60.79 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PRSS50, serine protease 50
  • Vertebrate Orthologs
    6
  • Human Ortholog
    PRSS50, serine protease 50
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CT20, TSP50
  • Links
    NCBI Gene ID: 29122
    neXtProt AC: NX_Q9UI38
    UniProt: Q9UI38

  • Chr Location
    3p21.31; chr3:46712116-46717883 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000052497 VEGA Gene Model | MGI Sequence Detail 6663 C57BL/6J ±  kb
    transcript OTTMUST00000131647 VEGA | MGI Sequence Detail 1456 Not Applicable  
    polypeptide OTTMUSP00000070336 VEGA | MGI Sequence Detail 439 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      115 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 4
      Primer pair 1

      Microarray probesets 1
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 1
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:13132 DEOL MS, et al., The spinner mouse. J Hered. 1962 May-Jun;53:133-6
    • Latest
      J:225652 Harten SK, et al., The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers. BMC Biol. 2015;13:21

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    Funding Information
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    last database update
    06/12/2018
    MGI 6.12
    The Jackson Laboratory