Prss50 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prss50
serine protease 50
MGI:2447303

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prss50^em1Cajj/Prss50^em1Cajj involves: C57BL/6J	abnormal seminiferous tubule morphology	J:305434
	abnormal sperm annulus morphology	J:305434
	abnormal sperm axoneme morphology	J:305434
	abnormal spermatid morphology	J:305434
	absent sperm flagellum	J:305434
	absent sperm mitochondrial sheath	J:305434
	asthenozoospermia	J:305434
	decreased hyperactivated sperm motility	J:305434
	decreased litter size	J:305434
	decreased sperm progressive motility	J:305434
	normal homeostasis/metabolism phenotype	J:305434
	immotile sperm	J:305434
	male infertility	J:305434
	multi-headed sperm	J:305434
	multiflagellated sperm	J:305434
	reduced male fertility	J:305434
	teratozoospermia	J:305434
Prss50^{tm1a(EUCOMM)Hmgu}/Prss50^{tm1a(EUCOMM)Hmgu} C57BL/6N-Prss50^{tm1a(EUCOMM)Hmgu}/H	abnormal bone mineralization	J:165965
	decreased bone mineral density	J:165965
	decreased CD8-positive, alpha-beta T cell number	J:165965
	decreased T cell number	J:165965

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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