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Tbc1d25 Gene Detail
Summary
  • Symbol
    Tbc1d25
  • Name
    TBC1 domain family, member 25
  • Synonyms
    6330576A08Rik, DXHXS7927e, mMg81, Oatl1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444862
    NCBI Gene: 209815
Location & Maps
more
  • Genetic Map
    Chromosome X, 3.69 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TBC1D25, TBC1 domain family member 25
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TBC1D25, TBC1 domain family member 25
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MG81, OATL1
  • Links
    NCBI Gene ID: 4943
    neXtProt AC: NX_Q3MII6

  • Chr Location
    Xp11.23; chrX:48539687-48562609 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018118 VEGA Gene Model | MGI Sequence Detail 21710 C57BL/6J ±  kb
transcript OTTMUST00000043740 VEGA | MGI Sequence Detail 2648 Not Applicable  
polypeptide OTTMUSP00000019638 VEGA | MGI Sequence Detail 742 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    71 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000016109 TBC1 domain family member 25
  • InterPro Domains
    IPR000195 Rab-GTPase-TBC domain
Molecular
Reagents
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  • All nucleic 33
    Genomic 2
    cDNA 30
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1099472
References
more
  • Summaries
    All 32
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:55860 Derry JM, et al., Mutations in a delta 8-delta 7 sterol isomerase in the tattered mouse and X-linked dominant chondrodysplasia punctata. jderry@immunex.com. Nat Genet. 1999 Jul;22(3):286-90
  • Latest
    J:170318 Itoh T, et al., OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation. J Cell Biol. 2011 Mar 7;192(5):839-53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory