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Tbc1d25 Gene Detail
Summary
  • Symbol
    Tbc1d25
  • Name
    TBC1 domain family, member 25
  • Synonyms
    6330576A08Rik, DXHXS7927e, mMg81, Oatl1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444862
    NCBI Gene: 209815
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:8154472-8176181 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 3.69 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    71 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444862
protein coding gene ChrX:8154470-8176181 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035542
protein coding gene ChrX:2801974-2825268 (-)
A/J MGP_AJ_G0035519
protein coding gene ChrX:2776254-2799735 (-)
AKR/J MGP_AKRJ_G0035452
protein coding gene ChrX:2892727-2915120 (-)
BALB/cJ MGP_BALBcJ_G0035516
protein coding gene ChrX:2774496-2796455 (-)
C3H/HeJ MGP_C3HHeJ_G0035224
protein coding gene ChrX:2858996-2882221 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036040
protein coding gene ChrX:2896218-2919830 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032915
protein coding gene ChrX:2301433-2324334 (-)
CAST/EiJ MGP_CASTEiJ_G0034525
protein coding gene ChrX:2745284-2767506 (-)
CBA/J MGP_CBAJ_G0035194
protein coding gene ChrX:3048012-3074069 (-)
DBA/2J MGP_DBA2J_G0035351
protein coding gene ChrX:2762227-2784103 (-)
FVB/NJ MGP_FVBNJ_G0035298
protein coding gene ChrX:2728458-2750843 (-)
LP/J MGP_LPJ_G0035428
protein coding gene ChrX:2822343-2843219 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035338
protein coding gene ChrX:2996503-3018223 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036058
protein coding gene ChrX:2783066-2804622 (-)
PWK/PhJ MGP_PWKPhJ_G0034225
protein coding gene ChrX:2704411-2726795 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034064
protein coding gene ChrX:2761648-2782866 (-)
WSB/EiJ MGP_WSBEiJ_G0034648
protein coding gene ChrX:2787155-2809341 (-)



Homology
more
  • Human Ortholog
    TBC1D25, TBC1 domain family member 25
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TBC1D25, TBC1 domain family member 25
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MG81, OATL1
  • Links
    NCBI Gene ID: 4943
    neXtProt AC: NX_Q3MII6
    UniProt: Q3MII6

  • Chr Location
    Xp11.23; chrX:48539687-48562609 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039201 Ensembl Gene Model | MGI Sequence Detail 21710 C57BL/6J ±  kb
transcript ENSMUST00000039892 Ensembl | MGI Sequence Detail 2648 Not Applicable  
polypeptide ENSMUSP00000047838 Ensembl | MGI Sequence Detail 742 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    Genomic 2
    cDNA 31
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1099472
References
more
  • Summaries
    All 33
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:55860 Derry JM, et al., Mutations in a delta 8-delta 7 sterol isomerase in the tattered mouse and X-linked dominant chondrodysplasia punctata. jderry@immunex.com. Nat Genet. 1999 Jul;22(3):286-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory