Tbc1d25 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tbc1d25
TBC1 domain family, member 25
MGI:2444862

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tbc1d25^em1(IMPC)Tcp/Y C57BL/6NCrl-Tbc1d25^em1(IMPC)Tcp/Tcp	abnormal retina morphology	J:211773
Tbc1d25^em1(IMPC)Tcp/Tbc1d25^em1(IMPC)Tcp C57BL/6NCrl-Tbc1d25^em1(IMPC)Tcp/Tcp	abnormal retina morphology	J:211773
	decreased grip strength	J:211773
Tbc1d25^{Gt(IST10205D5)Tigm}/Y involves: C57BL/6N	cardiac fibrosis	J:295960
	cardiac hypertrophy	J:295960
	cardiac interstitial fibrosis	J:295960
	decreased cardiac muscle contractility	J:295960
	decreased ventricle muscle contractility	J:295960
	enlarged heart	J:295960
	increased heart weight	J:295960
	increased lung weight	J:295960
	increased myocardial fiber size	J:295960
	increased response of heart to induced stress	J:295960

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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