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Zfp189 Gene Detail
Summary
  • Symbol
    Zfp189
  • Name
    zinc finger protein 189
  • Synonyms
    C430015I23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444707
    NCBI Gene: 230162
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:49521176-49531517 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 26.55 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444707
protein coding gene Chr4:49521176-49531558 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028283
protein coding gene Chr4:48003209-48014246 (+)
A/J MGP_AJ_G0028243
protein coding gene Chr4:46224110-46235083 (+)
AKR/J MGP_AKRJ_G0028192
protein coding gene Chr4:47441421-47451761 (+)
BALB/cJ MGP_BALBcJ_G0028262
protein coding gene Chr4:46332826-46343082 (+)
C3H/HeJ MGP_C3HHeJ_G0027983
protein coding gene Chr4:47992884-48007491 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028703
protein coding gene Chr4:49731948-49742966 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026012
protein coding gene Chr4:43428901-43441023 (+)
CAST/EiJ MGP_CASTEiJ_G0027422
protein coding gene Chr4:47565178-47579000 (+)
CBA/J MGP_CBAJ_G0027949
protein coding gene Chr4:51411507-51443962 (+)
DBA/2J MGP_DBA2J_G0028099
protein coding gene Chr4:46109936-46120288 (+)
FVB/NJ MGP_FVBNJ_G0028066
protein coding gene Chr4:45373617-45383721 (+)
LP/J MGP_LPJ_G0028198
protein coding gene Chr4:48081165-48092346 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028090
protein coding gene Chr4:54349394-54361168 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028738
protein coding gene Chr4:47634853-47645164 (+)
PWK/PhJ MGP_PWKPhJ_G0027147
protein coding gene Chr4:46185611-46199916 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026975
protein coding gene Chr4:47022539-47034404 (+)
WSB/EiJ MGP_WSBEiJ_G0027500
protein coding gene Chr4:47541814-47552784 (+)



Homology
more
  • Human Ortholog
    ZNF189, zinc finger protein 189
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ZNF189, zinc finger protein 189
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 7743
    neXtProt AC: NX_O75820
    UniProt: O75820

  • Chr Location
    9q31.1; chr9:101398830-101410660 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039634 Ensembl Gene Model | MGI Sequence Detail 10342 C57BL/6J ±  kb
transcript ENSMUST00000107696 Ensembl | MGI Sequence Detail 2965 Not Applicable  
polypeptide ENSMUSP00000103324 Ensembl | MGI Sequence Detail 608 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 2
Other
Accession IDs
less
MGI:2140639
References
more
  • Summaries
    All 24
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:281648 Lorsch ZS, et al., Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex. Nat Neurosci. 2019 Sep;22(9):1413-1423

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/10/2020
MGI 6.16
The Jackson Laboratory