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Aldh1l2 Gene Detail
Summary
  • Symbol
    Aldh1l2
  • Name
    aldehyde dehydrogenase 1 family, member L2
  • Synonyms
    D330038I09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444680
    NCBI Gene: 216188
  • Gene Overview
    MyGene.info: ALDH1L2
Location & Maps
more
  • Sequence Map
    Chr10:83487450-83534140 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      46691 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 41.27 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ALDH1L2, aldehyde dehydrogenase 1 family member L2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ALDH1L2, aldehyde dehydrogenase 1 family member L2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    mtFDH
  • Links
    NCBI Gene ID: 160428
    neXtProt AC: NX_Q3SY69

  • Chr Location
    12q23.3; chr12:105019784-105084583 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Aldh1l2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024804 VEGA Gene Model | MGI Sequence Detail 46691 C57BL/6J ±  kb
transcript OTTMUST00000061092 VEGA | MGI Sequence Detail 6027 Not Applicable  
polypeptide OTTMUSP00000029894 VEGA | MGI Sequence Detail 923 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    208 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032529 mitochondrial 10-formyltetrahydrofolate dehydrogenase
  • EC
  • InterPro Domains
    IPR011407 10-formyltetrahydrofolate dehydrogenase
    IPR016163 Aldehyde dehydrogenase, C-terminal
    IPR016160 Aldehyde dehydrogenase, cysteine active site
    IPR015590 Aldehyde dehydrogenase domain
    IPR029510 Aldehyde dehydrogenase, glutamic acid active site
    IPR016162 Aldehyde dehydrogenase N-terminal domain
    IPR016161 Aldehyde/histidinol dehydrogenase
    IPR005793 Formyl transferase, C-terminal
    IPR011034 Formyl transferase, C-terminal-like
    IPR002376 Formyl transferase, N-terminal
    IPR006162 Phosphopantetheine attachment site
    IPR009081 Phosphopantetheine binding ACP domain
    IPR001555 Phosphoribosylglycinamide formyltransferase, active site
Molecular
Reagents
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  • All nucleic 43
    cDNA 43

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory