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Aldh1l2 Gene Detail
Summary
  • Symbol
    Aldh1l2
  • Name
    aldehyde dehydrogenase 1 family, member L2
  • Synonyms
    D330038I09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444680
    NCBI Gene: 216188
  • Gene Overview
    MyGene.info: ALDH1L2
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:83487450-83534140 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 41.27 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    208 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444680
protein coding gene Chr10:83487447-83534151 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017586
protein coding gene Chr10:84302194-84344949 (-)
A/J MGP_AJ_G0017566
protein coding gene Chr10:81450491-81494569 (-)
AKR/J MGP_AKRJ_G0017525
protein coding gene Chr10:83701295-83747804 (-)
BALB/cJ MGP_BALBcJ_G0017529
protein coding gene Chr10:81693769-81745669 (-)
C3H/HeJ MGP_C3HHeJ_G0017351
protein coding gene Chr10:83794727-83842239 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017986
protein coding gene Chr10:87199058-87248525 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015670
protein coding gene Chr10:77145418-77193226 (-)
CAST/EiJ MGP_CASTEiJ_G0016918
protein coding gene Chr10:83673421-83716824 (-)
CBA/J MGP_CBAJ_G0017321
protein coding gene Chr10:90814399-90868251 (-)
DBA/2J MGP_DBA2J_G0017427
protein coding gene Chr10:80603179-80646541 (-)
FVB/NJ MGP_FVBNJ_G0017421
protein coding gene Chr10:79838880-79884881 (-)
LP/J MGP_LPJ_G0017499
protein coding gene Chr10:84941152-84987208 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017449
protein coding gene Chr10:92481426-92527759 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018023
protein coding gene Chr10:83640993-83684182 (-)
PWK/PhJ MGP_PWKPhJ_G0016699
protein coding gene Chr10:80466464-80514640 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016489
protein coding gene Chr10:82244601-82289647 (-)
WSB/EiJ MGP_WSBEiJ_G0016977
protein coding gene Chr10:83650939-83699030 (-)



Homology
more
  • Human Ortholog
    ALDH1L2, aldehyde dehydrogenase 1 family member L2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ALDH1L2, aldehyde dehydrogenase 1 family member L2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    mtFDH
  • Links
    NCBI Gene ID: 160428
    neXtProt AC: NX_Q3SY69
    UniProt: Q3SY69

  • Chr Location
    12q23.3; chr12:105019784-105084609 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020256 Ensembl Gene Model | MGI Sequence Detail 46691 C57BL/6J ±  kb
transcript ENSMUST00000020497 Ensembl | MGI Sequence Detail 6027 Not Applicable  
polypeptide ENSMUSP00000020497 Ensembl | MGI Sequence Detail 923 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032529 mitochondrial 10-formyltetrahydrofolate dehydrogenase
  • EC
  • InterPro Domains
    IPR011407 10-formyltetrahydrofolate dehydrogenase
    IPR036736 ACP-like superfamily
    IPR016163 Aldehyde dehydrogenase, C-terminal
    IPR016160 Aldehyde dehydrogenase, cysteine active site
    IPR015590 Aldehyde dehydrogenase domain
    IPR029510 Aldehyde dehydrogenase, glutamic acid active site
    IPR016162 Aldehyde dehydrogenase, N-terminal
    IPR016161 Aldehyde/histidinol dehydrogenase
    IPR005793 Formyl transferase, C-terminal
    IPR037022 Formyl transferase, C-terminal domain superfamily
    IPR011034 Formyl transferase-like, C-terminal domain superfamily
    IPR002376 Formyl transferase, N-terminal
    IPR036477 Formyl transferase, N-terminal domain superfamily
    IPR006162 Phosphopantetheine attachment site
    IPR009081 Phosphopantetheine binding ACP domain
    IPR001555 Phosphoribosylglycinamide formyltransferase, active site
Molecular
Reagents
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  • All nucleic 44
    cDNA 44

    Microarray probesets 2
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory