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Cilp Gene Detail
Summary
  • Symbol
    Cilp
  • Name
    cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • Synonyms
    C130036G17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444507
    NCBI Gene: 214425
  • Gene Overview
    MyGene.info: CILP
Location & Maps
more
  • Sequence Map
    Chr9:65265180-65280605 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      15426 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 35.20 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CILP, cartilage intermediate layer protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CILP, cartilage intermediate layer protein
    Orthology source: HomoloGene
  • Synonyms
    CILP-1, HsT18872
  • Links
    NCBI Gene ID: 8483
    neXtProt AC: NX_O75339

  • Chr Location
    15q22; chr15:65195999-65211502 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2679
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: CILP
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human CILP associations

Human Disease Mouse Models
       Intervertebral Disc Disease; IDD   OMIM: 603932
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Targeted
    5
  • Genomic Mutations
    1 involving Cilp
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016695 VEGA Gene Model | MGI Sequence Detail 15426 C57BL/6J ±  kb
transcript OTTMUST00000040435 VEGA | MGI Sequence Detail 4153 Not Applicable  
polypeptide OTTMUSP00000018063 VEGA | MGI Sequence Detail 1250 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    121 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:209494 Rolfe RA, et al., Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways. BMC Genomics. 2014;15:48

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory