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Cilp
Gene Detail
Symbol

Name
ID
Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
MGI:2444507
Synonyms
C130036G17Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
35.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:65265180-65280605 bp, + strand
From VEGA annotation of GRCm38

  15426 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2679  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CILP
Gene Tree: Cilp

Human
homologs
CILP, cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 8483
neXtProt AC: NX_O75339

Human Synonyms: CILP-1, HsT18872

Human Chr (Location): 15q22; chr15:65195999-65211502 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CILP

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cilp interacts with 406 markers (Mir7-2, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process negative regulation of insulin-like growth factor receptor signaling pathway
Component extracellular exosome, extracellular matrix, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (57)    Tissues (5)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 57
cDNA source data(20)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cilp ; ZFIN cilp    NEW 
Molecular
reagents
All nucleic(20) cDNA(20)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000016695 (Evidence)
Ensembl Gene Model ENSMUSG00000042254 (Evidence)
Entrez Gene 214425 (Evidence)
UniGene 138455
DFCI TC1584793
DoTS DT.101324835, DT.40152322
NIA Mouse Gene Index U010632
Consensus CDS Project CCDS23287.1
International Mouse Phenotyping Consortium Status Cilp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016695 VEGA Gene Model | MGI Sequence Detail 15426 C57BL/6J ±  kb
transcript OTTMUST00000040435 VEGA | MGI Sequence Detail 4153 Not Applicable 
polypeptide OTTMUSP00000018063 VEGA | MGI Sequence Detail 1250 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(121 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003598 Immunoglobulin subtype 2
InterPro IPR000884 Thrombospondin, type 1 repeat
InterPro IPR025155 WxxW domain
Protein Ontology PR:000005495 cartilage intermediate layer protein 1
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:209494 Rolfe RA, et al., Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways. BMC Genomics. 2014;15:48
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory