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Cfap65 Gene Detail
Summary
  • Symbol
    Cfap65
  • Name
    cilia and flagella associated protein 65
  • Synonyms
    B230363K08Rik, Ccdc108
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444274
    NCBI Gene: 241116
Location & Maps
more
  • Sequence Map
    Chr1:74902071-74935599 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33529 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 38.54 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CFAP65, cilia and flagella associated protein 65
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CFAP65, cilia and flagella associated protein 65
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCDC108
  • Links
    NCBI Gene ID: 255101
    neXtProt AC: NX_Q6ZU64
    UniProt: Q6ZU64

  • Chr Location
    2q35; chr2:219002846-219043142 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 28093
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CFAP65
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026700 VEGA Gene Model | MGI Sequence Detail 33529 C57BL/6J ±  kb
transcript OTTMUST00000066060 VEGA | MGI Sequence Detail 5727 Not Applicable  
polypeptide OTTMUSP00000033030 VEGA | MGI Sequence Detail 1847 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    199 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000032830 coiled-coil domain-containing protein 108
  • InterPro Domains
    IPR031549 Abnormal spindle-like microcephaly-associated protein, ASH domain
    IPR013783 Immunoglobulin-like fold
Molecular
Reagents
less
  • All nucleic 8
    Genomic 1
    cDNA 7

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory