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Poglut1
Gene Detail
Symbol

Name
ID
Poglut1
protein O-glucosyltransferase 1
MGI:2444232
Synonyms
9630046K23Rik, Ktelc1, Rumi
Feature Type
protein coding gene
Genetic Map
Chromosome 16
26.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:38525137-38550258 bp, - strand
From VEGA annotation of GRCm38

  25122 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41353  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Poglut1

Human
homologs
Human Homolog POGLUT1, protein O-glucosyltransferase 1
NCBI Gene ID 56983
neXtProt AC  NX_Q8NBL1
Human Synonyms  C3orf9, CLP46, hCLP46, KDELCL1, KTELC1, MDSRP, Rumi
Human Chr (Location)  3q13.33; chr3:119468938-119494708 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human POGLUT1
Mutations,
alleles, and
phenotypes
All mutations/alleles(91) : Gene trapped(89) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trapped allele exhibit complete embryonic lethality during organogenesis, embryonic growth retardation, caudal body truncation, and severe defects in neural tube development, somitogenesis, cardiogenesis, and vascular remodeling.
 
Interactions
Poglut1 interacts with 195 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (16)    Tissues (12)    Images (8)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 3
Western blot 10
RT-PCR 3
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(13) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000028147 (Evidence)
Ensembl Gene ModelENSMUSG00000034064 (Evidence)
Entrez Gene224143 (Evidence)
DFCITC1620762, TC1620124, TC1574772, TC1611864
DoTSDT.97413848, DT.87054170, DT.94259663
NIA Mouse Gene IndexU037039
EC2.4.1.-, 2.4.2.26
Consensus CDS ProjectCCDS28170.1
International Mouse Knockout Project StatusPoglut1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028147 VEGA Gene Model | MGI Sequence Detail 25122 C57BL/6J ±  kb
transcript OTTMUST00000069719 VEGA | MGI Sequence Detail 2758 Not Applicable 
polypeptide OTTMUSP00000035454 VEGA | MGI Sequence Detail 392 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(128 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006598 Lipopolysaccharide-modifying protein
Protein Ontology PR:000009593 protein O-glucosyltransferase 1
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:177336 Takeuchi H, et al., Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase. Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16600-5
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory