Poglut1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Poglut1
protein O-glucosyltransferase 1
MGI:2444232

26 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Poglut1^em1(IMPC)Bay/Poglut1⁺ C57BL/6N-Poglut1^em1(IMPC)Bay/Bay	abnormal retina outer nuclear layer morphology	J:211773
Poglut1^em1(IMPC)Bay/Poglut1^em1(IMPC)Bay C57BL/6N-Poglut1^em1(IMPC)Bay/Bay	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Poglut1^{Gt(IST10323G11)Tigm}/Poglut1^{Gt(IST10323G11)Tigm} involves: C57BL/6N	abnormal cardiogenic plate morphology	J:171432
	abnormal developmental patterning	J:171432
	abnormal dorsal aorta morphology	J:171432
	abnormal ectoderm development	J:171432
	abnormal heart development	J:171432
	abnormal mesoderm development	J:171432
	abnormal neural fold formation	J:171432
	abnormal neural plate morphology	J:171432
	abnormal vascular development	J:171432
	abnormal vitelline vascular remodeling	J:171432
	abnormal vitelline vasculature morphology	J:171432
	absent intersomitic vessels	J:171432
	absent somites	J:171432
	cardia bifida	J:171432
	caudal body truncation	J:171432
	embryonic growth retardation	J:171432
	embryonic lethality during organogenesis, complete penetrance	J:171432
	failure of initiation of embryo turning	J:171432
Poglut1^wsnp/Poglut1^wsnp involves: C3H/HeJ * C57BL/6J	abnormal neural plate morphology	J:48268
	absent somites	J:48268
	decreased embryo size	J:48268
	decreased paraxial mesoderm size	J:48268
Poglut1^wsnp/Poglut1^wsnp involves: C3HeB/FeJ * C57BL/6J	decreased axial mesoderm size	J:98216
	decreased paraxial mesoderm size	J:98216
	embryonic growth arrest	J:98216
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:98216

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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