About   Help   FAQ
Bptf
Gene Detail
 Symbol
Name
ID
Bptf
bromodomain PHD finger transcription factor
MGI:2444008
Synonyms 9430093H17Rik, Falz, MGC:54978
Feature Type protein coding gene
Genetic Map
Chromosome 11
70.11 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:107033083-107132127 bp, - strand
From VEGA annotation of GRCm38

  99045 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:114397  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Bptf

Human
homologs
Human Homolog BPTF, bromodomain PHD finger transcription factor
NCBI Gene ID 2186
neXtProt AC  NX_Q12830
Human Synonyms  FAC1, FALZ, NURF301
Human Chr (Location)  17q24.3; chr17:67825528-67984378 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(56) : Gene trapped(54) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display embryonic lethality during organogenesis with embryonic growth arrest around early gastrulation and a greatly reduced ectoplacental cone.
 
Interactions
Bptf interacts with 433 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process anterior/posterior pattern specification, ATP catabolic process, ...
Component cytoplasm, microtubule cytoskeleton, ...
Function DNA-dependent ATPase activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (238)    Tissues (183)    Images (43)
Theiler Stages: 2, 3, 4, 5, 11, 13, 17, 19, 21, 22, 23, 27, 28
Assay TypeResults
RNA in situ 230
RT-PCR 8
cDNA source data(280)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(283) cDNA(282) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000003587 (Evidence)
Ensembl Gene ModelENSMUSG00000040481 (Evidence)
Entrez Gene207165 (Evidence)
UniGene343986
DFCITC1578224, TC1585470, TC1598755, TC1600911, TC1607824, TC1617312
DoTSDT.101189148, DT.521708, DT.91283914, DT.94168750, DT.94395528, DT.97346613, DT.97373860
NIA Mouse Gene IndexU041151
Consensus CDS ProjectCCDS48964.1
International Mouse Knockout Project StatusBptf
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003587 VEGA Gene Model | MGI Sequence Detail 99045 C57BL/6J ±  kb
transcript OTTMUST00000007729 VEGA | MGI Sequence Detail 12036 Not Applicable 
polypeptide OTTMUSP00000003750 VEGA | MGI Sequence Detail 3036 Not Applicable 

For the selected sequences
All sequences(117) RefSeq(37) UniProt(13)
Polymorphisms SNPs within 2kb(221 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001487 Bromodomain
InterPro IPR018359 Bromodomain, conserved site
InterPro IPR004022 DDT domain
InterPro IPR018500 DDT domain, subgroup
InterPro IPR018501 DDT domain superfamily
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000004799 nucleosome-remodeling factor subunit BPTF
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:168139 Landry JW, et al., Chromatin remodeling complex NURF regulates thymocyte maturation. Genes Dev. 2011 Feb 1;25(3):275-86
All references(47)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/26/2014
MGI 5.19
The Jackson Laboratory