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Aldh4a1 Gene Detail
Summary
  • Symbol
    Aldh4a1
  • Name
    aldehyde dehydrogenase 4 family, member A1
  • Synonyms
    A930035F14Rik, Ahd1, Ahd-1, ALDH4, P5CDH, Ssdh1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443883
    NCBI Gene: 212647
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:139622871-139649691 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 70.79 cM
  • Mapping Data
    29 experiments
Strain
Comparison
more
  • SNPs within 2kb
    437 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443883
protein coding gene Chr4:139622866-139649691 (.)
129S1/SvImJ MGP_129S1SvImJ_G0029021
protein coding gene Chr4:142469305-142497807 (+)
A/J MGP_AJ_G0028980
protein coding gene Chr4:136345297-136372181 (+)
AKR/J MGP_AKRJ_G0028932
protein coding gene Chr4:140249297-140282171 (+)
BALB/cJ MGP_BALBcJ_G0029004
protein coding gene Chr4:137022139-137050187 (+)
C3H/HeJ MGP_C3HHeJ_G0028718
protein coding gene Chr4:140641662-140669739 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029445
protein coding gene Chr4:147522435-147551285 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026716
protein coding gene Chr4:129296066-129322977 (+)
CAST/EiJ MGP_CASTEiJ_G0028150
protein coding gene Chr4:138833626-138860580 (+)
CBA/J MGP_CBAJ_G0028682
protein coding gene Chr4:151765065-151791931 (+)
DBA/2J MGP_DBA2J_G0028832
protein coding gene Chr4:136745328-136772548 (+)
FVB/NJ MGP_FVBNJ_G0028799
protein coding gene Chr4:135781177-135807868 (+)
LP/J MGP_LPJ_G0028931
protein coding gene Chr4:142551723-142578603 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028825
protein coding gene Chr4:155657360-155685507 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029483
protein coding gene Chr4:140776831-140805714 (+)
PWK/PhJ MGP_PWKPhJ_G0027871
protein coding gene Chr4:133593551-133620647 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027696
protein coding gene Chr4:136570131-136597029 (+)
WSB/EiJ MGP_WSBEiJ_G0028228
protein coding gene Chr4:141042318-141069206 (+)



Homology
more
  • Human Ortholog
    ALDH4A1, aldehyde dehydrogenase 4 family member A1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ALDH4A1, aldehyde dehydrogenase 4 family member A1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ALDH4, P5CD, P5CDh
  • Links
    NCBI Gene ID: 8659
    neXtProt AC: NX_P30038
    UniProt: P30038

  • Chr Location
    1p36.13; chr1:18871430-18902799 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 212647 NCBI Gene Model | MGI Sequence Detail 26821 C57BL/6J ±  kb
transcript NM_175438 RefSeq | MGI Sequence Detail 3355 C57BL/6  
polypeptide Q8CHT0 UniProt | EBI | MGI Sequence Detail 562 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 170
    cDNA 169
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-1205, MGD-MRK-1212, MGD-MRK-16330, MGI:1353453, MGI:99552
References
more
  • Summaries
    All 62
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:6127 Holmes RS, Genetics and ontogeny of aldehyde dehydrogenase isozymes in the mouse: localization of Ahd-1 encoding the mitochondrial isozyme on chromosome 4. Biochem Genet. 1978 Dec;16(11-12):1207-18
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory