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Ppfia2 Gene Detail
Summary
  • Symbol
    Ppfia2
  • Name
    protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
  • Synonyms
    E130120L08Rik, Liprin-alpha2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443834
    NCBI Gene: 327814
Location & Maps
more
  • Sequence Map
    Chr10:106470310-106933467 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      463158 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 55.39 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PPFIA2, PTPRF interacting protein alpha 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PPFIA2, PTPRF interacting protein alpha 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 8499
    neXtProt AC: NX_O75334

  • Chr Location
    12q21.31; chr12:81257975-81759548 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Ppfia2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053825 Ensembl Gene Model | MGI Sequence Detail 463158 C57BL/6J ±  kb
transcript ENSMUST00000029404 Ensembl | MGI Sequence Detail 6436 Not Applicable  
polypeptide ENSMUSP00000029404 Ensembl | MGI Sequence Detail 1257 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1993 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 30
    Genomic 1
    cDNA 29

    Microarray probesets 3
Other
Accession IDs
less
MGI:2445215
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:221584 Quesnel-Vallieres M, et al., Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes Dev. 2015 Apr 1;29(7):746-59

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory