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Iqcb1 Gene Detail
Summary
  • Symbol
    Iqcb1
  • Name
    IQ calmodulin-binding motif containing 1
  • Synonyms
    6820449I09Rik, NPHP5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443764
    NCBI Gene: 320299
  • Gene Overview
    MyGene.info: IQCB1
Location & Maps
more
  • Sequence Map
    Chr16:36828385-36872721 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      44337 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 26.11 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    IQCB1, IQ motif containing B1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    IQCB1, IQ motif containing B1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NPHP5, PIQ, SLSN5
  • Links
    NCBI Gene ID: 9657
    neXtProt AC: NX_Q15051

  • Chr Location
    3q13.33; chr3:121769763-121835079 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human IQCB1 associations

Human Disease Mouse Models
       Senior-Loken Syndrome 5; SLSN5   OMIM: 609254
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024358 VEGA Gene Model | MGI Sequence Detail 44337 C57BL/6J ±  kb
transcript OTTMUST00000059670 VEGA | MGI Sequence Detail 2257 Not Applicable  
polypeptide OTTMUSP00000029045 VEGA | MGI Sequence Detail 598 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    41 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000031856 IQ calmodulin-binding motif-containing protein 1
  • InterPro Domains
    IPR016024 Armadillo-type fold
    IPR028765 IQ calmodulin-binding motif-containing protein 1
    IPR000048 IQ motif, EF-hand binding site
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 41
    cDNA 41

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146598
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173396 Sang L, et al., Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 2011 May 13;145(4):513-28

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory