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Iqcb1
Gene Detail
 Symbol
Name
ID
Iqcb1
IQ calmodulin-binding motif containing 1
MGI:2443764
Synonyms 6820449I09Rik, NPHP5
Feature Type protein coding gene
Genetic Map
Chromosome 16
26.11 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:36828385-36872721 bp, + strand
From VEGA annotation of GRCm38

  44337 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8766  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Iqcb1

Human
homologs
Human Homolog IQCB1, IQ motif containing B1
NCBI Gene ID 9657
neXtProt AC  NX_Q15051
Human Synonyms  NPHP5, PIQ, SLSN5
Human Chr (Location)  3q13.33; chr3:121769763-121835079 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human IQCB1
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Iqcb1 interacts with 191 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process cilium assembly, maintenance of organ identity, ...
Component centrosome, cytoplasm, ...
Function calmodulin binding, enzyme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (38)    Tissues (12)    Images (28)
Theiler Stages: 11, 13, 15, 17, 23, 28
Assay TypeResults
Immunohistochemistry 4
RNA in situ 30
Western blot 4
cDNA source data(41)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(41) cDNA(41)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000024358 (Evidence)
Ensembl Gene ModelENSMUSG00000022837 (Evidence)
Entrez Gene320299 (Evidence)
UniGene222934
DFCITC1579019, TC1589901, TC1624890
DoTSDT.485387, DT.55223853, DT.91587535, DT.99839381
NIA Mouse Gene IndexU017079
Consensus CDS ProjectCCDS28157.1
International Mouse Knockout Project StatusIqcb1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024358 VEGA Gene Model | MGI Sequence Detail 44337 C57BL/6J ±  kb
transcript OTTMUST00000059670 VEGA | MGI Sequence Detail 2257 Not Applicable 
polypeptide OTTMUSP00000029045 VEGA | MGI Sequence Detail 598 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(11) UniProt(1)
Polymorphisms SNPs within 2kb(43 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR000048 IQ motif, EF-hand binding site
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000031856 IQ calmodulin-binding motif-containing protein 1
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173396 Sang L, et al., Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 2011 May 13;145(4):513-28
All references(31)
Other
accession IDs
MGI:2146598

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory