Iqcb1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Iqcb1
IQ calmodulin-binding motif containing 1
MGI:2443764

20 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Iqcb1^em1(IMPC)Bay/Iqcb1⁺ C57BL/6N-Iqcb1^em1(IMPC)Bay/Bay	decreased total body fat amount	J:211773
	increased cornea thickness	J:211773
	increased heart left ventricle size	J:211773
	increased lean body mass	J:211773
	thick ventricular wall	J:211773
Iqcb1^em1(IMPC)Bay/Iqcb1^em1(IMPC)Bay C57BL/6N-Iqcb1^em1(IMPC)Bay/Bay	preweaning lethality, incomplete penetrance	J:211773
Iqcb1^{tm1a(EUCOMM)Hmgu}/Iqcb1^{tm1a(EUCOMM)Hmgu} involves: C57BL/6J * C57BL/6N	abnormal eye physiology	J:239714
	abnormal photoreceptor outer segment disc membrane morphology	J:239714
	abnormal retina cone cell morphology	J:239714
	abnormal retina photoreceptor morphology	J:239714
	abnormal retina rod cell morphology	J:239714
	abnormal retina rod cell outer segment morphology	J:239714
	absent a-wave	J:239714
	absent b-wave	J:239714
	blindness	J:239714
	normal renal/urinary system phenotype	J:239714
	retina cone cell degeneration	J:239714
	retina degeneration	J:239714
	retina photoreceptor degeneration	J:239714
	retina rod cell degeneration	J:239714
Iqcb1^{tm1a(EUCOMM)Hmgu}/Iqcb1^{tm1a(EUCOMM)Hmgu} Tg(CAG-EGFP/CETN2)3-4Jgg/0 involves: BALB/c * C57BL/6 * C57BL/6J * C57BL/6N	abnormal photoreceptor outer segment disc membrane morphology	J:239714
	abnormal retina photoreceptor morphology	J:239714

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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