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Numa1
Gene Detail
 Symbol
Name
ID
Numa1
nuclear mitotic apparatus protein 1
MGI:2443665
Synonyms 6720401E04Rik
Feature Type protein coding gene
Genetic Map
Chromosome 7
54.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:101969843-102014959 bp, + strand
From VEGA annotation of GRCm38

  45117 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38150  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Numa1

Human
homologs
Human Homolog NUMA1, nuclear mitotic apparatus protein 1
NCBI Gene ID 4926
neXtProt AC  NX_Q14980
Human Synonyms  NUMA
Human Chr (Location)  11q13; chr11:72002864-72080693 (-)  GRCh38
Alleles
and
phenotypes
All alleles(102) : Gene trapped(99) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out or hypomorphic allele exhibit embryonic lethality by E9.5.
 
Phenotype Images(2)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process establishment of mitotic spindle orientation, lung epithelial cell differentiation
Component apical part of cell, cell, ...
Function microtubule binding, tubulin binding
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (37)    Tissues (9)    Images (23)
Theiler Stages: 20, 21, 22, 23, 24, 26, 28
Assay TypeResults
RNA in situ 37
cDNA source data(262)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(262) cDNA(262)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000035829 (Evidence)
Ensembl Gene ModelENSMUSG00000066306 (Evidence)
Entrez Gene101706 (Evidence)
UniGene27259
DFCITC1572764, TC1589340
DoTSDT.494364, DT.55247198, DT.94203977, DT.94203979
NIA Mouse Gene IndexU250336
Consensus CDS ProjectCCDS40046.1
International Mouse Knockout Project StatusNuma1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035829 VEGA Gene Model | MGI Sequence Detail 45117 C57BL/6J ±  kb
transcript OTTMUST00000091764 VEGA | MGI Sequence Detail 7153 Not Applicable 
polypeptide OTTMUSP00000050572 VEGA | MGI Sequence Detail 2094 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(22) UniProt(7)
Polymorphisms SNPs within 2kb(302 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026650 Golgin subfamily A member 3
Protein Ontology PR:000011503 nuclear mitotic apparatus protein 1
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:187021 Kolano A, et al., Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):E1858-67
All references(44)
Other
accession IDs
MGI:2137869, MGI:2142083, MGI:2142110

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory