Numa1
Gene Detail

Symbol Name ID

Numa1 nuclear mitotic apparatus protein 1 MGI:2443665

Synonyms

6720401E04Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 7

54.70 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr7:101969843-102014959 bp, + strand From VEGA annotation of GRCm38   45117 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:38150  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Numa1

Human homologs

Human Homolog		NUMA1, nuclear mitotic apparatus protein 1
NCBI Gene ID		4926
neXtProt AC		NX_Q14980
Human Synonyms		NUMA
Human Chr (Location)		11q13; chr11:71713911-71791573 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(102) : Targeted(3) Gene trapped(99)
 

Mice homozygous for a knock-out or hypomorphic allele exhibit embryonic lethality by E9.5.

 
Phenotype Images(2)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	establishment of mitotic spindle orientation, lung epithelial cell differentiation
Component	apical part of cell, cell, ...
Function	microtubule binding, tubulin binding

External Resources: FuncBase

Expression

Literature Summary: (6 records)
Data Summary: Results (37)    Tissues (9)    Images (23)
Theiler Stages: 20, 21, 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	37

cDNA source data(262)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(262) cDNA(262)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000035829 (Evidence)
Ensembl Gene Model	ENSMUSG00000066306 (Evidence)
Entrez Gene	101706 (Evidence)
UniGene	27259
DFCI	TC1572764, TC1589340
DoTS	DT.494364, DT.55247198, DT.94203977, DT.94203979
NIA Mouse Gene Index	U250336
Consensus CDS Project	CCDS40046.1
International Mouse Knockout Project Status	Numa1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035829	VEGA Gene Model | MGI Sequence Detail	45117	C57BL/6J
transcript	OTTMUST00000091764	VEGA | MGI Sequence Detail	7153	Not Applicable
polypeptide	OTTMUSP00000050572	VEGA | MGI Sequence Detail	2094	Not Applicable

All sequences(40) RefSeq(2) UniProt(7)

Polymorphisms

SNPs within 2kb(302 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR026650	Golgin subfamily A member 3
Protein Ontology	PR:000011503	nuclear mitotic apparatus protein 1

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:187021 Kolano A, et al., Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):E1858-67
All references(43)

Other accession IDs

MGI:2137869, MGI:2142083, MGI:2142110