Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including disordered domain specific binding activity; dynein complex binding activity; and microtubule binding activity. Involved in several processes, including establishment of mitotic spindle orientation; positive regulation of BMP signaling pathway; and positive regulation of keratinocyte differentiation. Acts upstream of or within lung epithelial cell differentiation. Located in several cellular components, including lateral cell cortex; mitotic spindle pole; and nuclear matrix. Is expressed in several structures, including 1st branchial arch mandibular component; brain ventricular layer; early embryo; facial prominence; and oocyte. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human NUMA1 (nuclear mitotic apparatus protein 1).