About   Help   FAQ
L3mbtl2
Gene Detail
Symbol

Name
ID
L3mbtl2
l(3)mbt-like 2 (Drosophila)
MGI:2443584
Synonyms
4732493N06Rik, m4mbt
Feature Type
protein coding gene
Genetic Map
Chromosome 15
38.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:81663889-81688315 bp, + strand
From VEGA annotation of GRCm38

  24427 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12882  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: L3mbtl2

Human
homologs
Human Homolog L3MBTL2, l(3)mbt-like 2 (Drosophila)
NCBI Gene ID 83746
neXtProt AC  NX_Q969R5
Human Synonyms  H-l(3)mbt-l, L3MBT
Human Chr (Location)  22q13.31-q13.33; chr22:41205309-41231271 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(34) : Gene trapped(29) Radiation induced(1) Targeted(4)
Genomic Mutations involving L3mbtl2 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
L3mbtl2 interacts with 108 markers (Mir1b, Mir10a, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process chromatin modification, regulation of transcription, DNA-templated, ...
Component nucleus
Function histone binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (16)    Tissues (16)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 16
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000038071 (Evidence)
Ensembl Gene ModelENSMUSG00000022394 (Evidence)
Entrez Gene214669 (Evidence)
DFCITC1702360, TC1574399
NIA Mouse Gene IndexU016466
Consensus CDS ProjectCCDS27669.1
International Mouse Knockout Project StatusL3mbtl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000038071 VEGA Gene Model | MGI Sequence Detail 24427 C57BL/6J ±  kb
transcript OTTMUST00000098040 VEGA | MGI Sequence Detail 2578 Not Applicable 
polypeptide OTTMUSP00000055023 VEGA | MGI Sequence Detail 739 Not Applicable 

For the selected sequences
All sequences(87) RefSeq(7) UniProt(13)
Polymorphisms
SNPs within 2kb(62 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004092 Mbt repeat
InterPro IPR012313 Zinc finger, FCS-type
Protein Ontology PR:000009641 lethal(3)malignant brain tumor-like protein 2
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory