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Gpr179 Gene Detail
Summary
  • Symbol
    Gpr179
  • Name
    G protein-coupled receptor 179
  • Synonyms
    5330439C02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443409
    NCBI Gene: 217143
  • Gene Overview
    MyGene.info: GPR179
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr11:97332109-97352077 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19969 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 60.95 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    GPR179, G protein-coupled receptor 179
  • Vertebrate Orthologs
    11
  • Human Ortholog
    GPR179, G protein-coupled receptor 179
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CSNB1E, GPR158L, GPR158L1
  • Links
    NCBI Gene ID: 440435
    neXtProt AC: NX_Q6PRD1
    UniProt: Q6PRD1

  • Chr Location
    17q12; chr17:38325610-38343810 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Gpr179 mouse models; 1 with human GPR179 associations

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit absence of b wave without retinal abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002518 VEGA Gene Model | MGI Sequence Detail 19969 C57BL/6J ±  kb
transcript OTTMUST00000035404 VEGA | MGI Sequence Detail 9219 Not Applicable  
polypeptide OTTMUSP00000046881 VEGA | MGI Sequence Detail 2293 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    200 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR017978 GPCR family 3, C-terminal
    IPR032964 Probable G-protein coupled receptor 179
Molecular
Reagents
less
  • All nucleic 6
    cDNA 5
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 2
    Phenotypes 20
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:256152 Wang Y, et al., The Auxiliary Calcium Channel Subunit alpha2delta4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors. Neuron. 2017 Mar 22;93(6):1359-1374.e6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/18/2018
MGI 6.12
The Jackson Laboratory