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Gpr179
Gene Detail
Symbol

Name
ID
Gpr179
G protein-coupled receptor 179
MGI:2443409
Synonyms
5330439C02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
60.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:97332109-97352077 bp, - strand
From VEGA annotation of GRCm38

  19969 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:34917  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 3 zebrafish

Gene Tree: Gpr179

Human
homologs
Human Homolog GPR179, G protein-coupled receptor 179
NCBI Gene ID 440435
neXtProt AC  NX_Q6PRD1
Human Synonyms  CSNB1E, GPR158L, GPR158L1
Human Chr (Location)  17q21.1; chr17:38325610-38343810 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human GPR179
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(5) Spontaneous(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit absence of b wave without retinal abnormalities.
 
Interactions
Gpr179 interacts with 332 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000002518 (Evidence)
Ensembl Gene ModelENSMUSG00000070337 (Evidence)
Entrez Gene217143 (Evidence)
DFCITC1591172, TC1619443
NIA Mouse Gene IndexU033338
Consensus CDS ProjectCCDS36292.1
International Mouse Knockout Project StatusGpr179
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002518 VEGA Gene Model | MGI Sequence Detail 19969 C57BL/6J ±  kb
transcript OTTMUST00000035404 VEGA | MGI Sequence Detail 9219 Not Applicable 
polypeptide OTTMUSP00000046881 VEGA | MGI Sequence Detail 2293 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(11) UniProt(4)
Polymorphisms
SNPs within 2kb(200 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000742 Epidermal growth factor-like domain
InterPro IPR017978 GPCR, family 3, C-terminal
Protein Ontology PR:000031583 G-protein coupled receptor 179
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:211063 Ray TA, et al., GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells. J Neurosci. 2014 Apr 30;34(18):6334-43
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory