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Gpr179
Gene Detail
Symbol

Name
ID
Gpr179
G protein-coupled receptor 179
MGI:2443409
Synonyms
5330439C02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
60.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:97332109-97352077 bp, - strand
From VEGA annotation of GRCm38

  19969 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:34917  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 3 zebrafish

HCOP human homology predictions: GPR179
Gene Tree: Gpr179

Human
homologs
GPR179, G protein-coupled receptor 179
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 440435
neXtProt AC: NX_Q6PRD1

Human Synonyms: CSNB1E, GPR158L, GPR158L1

Human Chr (Location): 17q21.1; chr17:38325610-38343810 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human GPR179

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(5) Spontaneous(1) Targeted(3)
Genomic Mutations involving Gpr179 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a knock-out allele exhibit absence of b wave without retinal abnormalities.
 
Interactions
Gpr179 interacts with 331 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process G-protein coupled receptor signaling pathway, protein localization to plasma membrane, ...
Component dendrite terminus, plasma membrane
Function protein binding
External Resources: FuncBase
Expression
cDNA source data(3)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase gpr179    NEW 
Molecular
reagents
All nucleic(3) cDNA(3)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000002518 (Evidence)
Ensembl Gene Model ENSMUSG00000070337 (Evidence)
Entrez Gene 217143 (Evidence)
DFCI TC1591172, TC1619443
NIA Mouse Gene Index U033338
Consensus CDS Project CCDS36292.1
International Mouse Phenotyping Consortium Status Gpr179
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002518 VEGA Gene Model | MGI Sequence Detail 19969 C57BL/6J ±  kb
transcript OTTMUST00000035404 VEGA | MGI Sequence Detail 9219 Not Applicable 
polypeptide OTTMUSP00000046881 VEGA | MGI Sequence Detail 2293 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(11) UniProt(2)
Polymorphisms
SNPs within 2kb(200 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000742 EGF-like domain
InterPro IPR017978 GPCR, family 3, C-terminal
Protein Ontology PR:000031583 G-protein coupled receptor 179
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:211063 Ray TA, et al., GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells. J Neurosci. 2014 Apr 30;34(18):6334-43
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory