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Gpr179 Gene Detail
Summary
  • Symbol
    Gpr179
  • Name
    G protein-coupled receptor 179
  • Synonyms
    5330439C02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443409
    NCBI Gene: 217143
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:97222935-97242903 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 60.95 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    198 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443409
protein coding gene Chr11:97222935-97243182 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019029
protein coding gene Chr11:99744176-99766457 (-)
A/J MGP_AJ_G0018997
protein coding gene Chr11:95645626-95665377 (-)
AKR/J MGP_AKRJ_G0018967
protein coding gene Chr11:98618069-98638170 (-)
BALB/cJ MGP_BALBcJ_G0018970
protein coding gene Chr11:96129600-96149882 (-)
C3H/HeJ MGP_C3HHeJ_G0018784
protein coding gene Chr11:98737155-98757227 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019422
protein coding gene Chr11:102843382-102866026 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017053
protein coding gene Chr11:93107606-93127683 (-)
CAST/EiJ MGP_CASTEiJ_G0018337
protein coding gene Chr11:99585831-99607146 (-)
CBA/J MGP_CBAJ_G0018755
protein coding gene Chr11:107087722-107108480 (-)
DBA/2J MGP_DBA2J_G0018863
protein coding gene Chr11:95202596-95222506 (-)
FVB/NJ MGP_FVBNJ_G0018852
protein coding gene Chr11:94683548-94704663 (-)
LP/J MGP_LPJ_G0018933
protein coding gene Chr11:100262940-100284437 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018879
protein coding gene Chr11:106958040-106977753 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019462
protein coding gene Chr11:98915255-98935955 (-)
PWK/PhJ MGP_PWKPhJ_G0018109
protein coding gene Chr11:96179290-96199411 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017899
protein coding gene Chr11:98626908-98646901 (-)
WSB/EiJ MGP_WSBEiJ_G0018387
protein coding gene Chr11:98815928-98835719 (-)



Homology
more
  • Human Ortholog
    GPR179, G protein-coupled receptor 179
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPR179, G protein-coupled receptor 179
  • Synonyms
    CSNB1E, GPR158L, GPR158L1
  • Links
    NCBI Gene ID: 440435
    neXtProt AC: NX_Q6PRD1
    UniProt: Q6PRD1

  • Chr Location
    17q12; chr17:38324571-38343956 (-)  GRCh38

Human Diseases
more
  • Diseases
    1 with Gpr179 mouse models; 1 with human GPR179 associations

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    28 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit absence of b wave without retinal abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070337 Ensembl Gene Model | MGI Sequence Detail 19969 C57BL/6J ±  kb
transcript ENSMUST00000093942 Ensembl | MGI Sequence Detail 9219 Not Applicable  
polypeptide ENSMUSP00000091474 Ensembl | MGI Sequence Detail 2293 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 5
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 49
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 8
    Phenotypes 28
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:340157 Wilmet B, et al., Mice Lacking Gpr179 with Complete Congenital Stationary Night Blindness Are a Good Model for Myopia. Int J Mol Sci. 2022 Dec 22;24(1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory