Gpr179^nob5
Spontaneous Allele Detail

Summary

• Symbol: Gpr179^nob5
• Name: G protein-coupled receptor 179; no b wave 5
• MGI ID: MGI:5431477
• Gene: Gpr179 Location: Chr11:97222935-97242903 bp, - strand Genetic Position: Chr11, 60.95 cM
• Alliance: Gpr179^nob5 page

Mutation origin

• Strain of Origin: C3H

Mutation description

• Allele Type: Spontaneous
• Mutation: Transposon insertion
• Mutation details: The ERV2 retroviral transposon inserted into intron 1. RT-PCR confirmed reduced transcript expression in the retina. (J:185567)
• Inheritance: Recessive

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr179 Mutation: 71 strains or lines available

Notes

This mutation has been found in C3H/HeN, but is absent from C3H/HeJ, C3H/HeOuJ, C3HeB/FeJ, C3H/HeSnJ (J:224435) and C3H/HeH (J:211946).

References

• Original: J:185567 Peachey NS, et al., GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness. Am J Hum Genet. 2012 Feb 10;90(2):331-9
• All: 15 reference(s)