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Mphosph9 Gene Detail
Summary
  • Symbol
    Mphosph9
  • Name
    M-phase phosphoprotein 9
  • Synonyms
    4930548D04Rik, 9630025B04Rik, B930097C17Rik, MPP9, MPP-9
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443138
    NCBI Gene: 269702
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:124389022-124466001 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 63.47 cM, cytoband F
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    467 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443138
 protein coding gene Chr5:124389022-124466035 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030091
 protein coding gene Chr5:128049250-128131105 (-)
A/J MGP_AJ_G0030056
 protein coding gene Chr5:122722098-122798717 (-)
AKR/J MGP_AKRJ_G0029992
 protein coding gene Chr5:126671882-126752350 (-)
BALB/cJ MGP_BALBcJ_G0030067
 protein coding gene Chr5:124057458-124132969 (-)
C3H/HeJ MGP_C3HHeJ_G0029784
 protein coding gene Chr5:127285939-127364472 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030520
 protein coding gene Chr5:133010708-133091538 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027746
 protein coding gene Chr5:117253676-117328889 (-)
CAST/EiJ MGP_CASTEiJ_G0029193
 protein coding gene Chr5:126402532-126481682 (-)
CBA/J MGP_CBAJ_G0029754
 protein coding gene Chr5:138241867-138324635 (-)
DBA/2J MGP_DBA2J_G0029904
 protein coding gene Chr5:122740924-122816570 (-)
FVB/NJ MGP_FVBNJ_G0029860
 protein coding gene Chr5:121776913-121852661 (-)
LP/J MGP_LPJ_G0029993
 protein coding gene Chr5:128596071-128679004 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029891
 protein coding gene Chr5:141817973-141900272 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030561
 protein coding gene Chr5:126292129-126367416 (-)
PWK/PhJ MGP_PWKPhJ_G0028907
 protein coding gene Chr5:121555762-121636449 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028744
 protein coding gene Chr5:123941959-124014202 (-)
WSB/EiJ MGP_WSBEiJ_G0029268
 protein coding gene Chr5:126963856-127040194 (-)



Homology
more
  • Human Ortholog
    MPHOSPH9, M-phase phosphoprotein 9
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MPHOSPH9, M-phase phosphoprotein 9
  • Synonyms
    MPP9, MPP-9
  • Links
    NCBI Gene ID: 10198
    neXtProt AC: NX_Q99550
    UniProt: Q99550

  • Chr Location
    12q24.31; chr12:123152320-123244014 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human MPHOSPH9 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit a twisted body axis at midgestation, decreased weight and an increased percentage of ciliated cells in the proximal and distal tubules.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    9
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    55
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 269702 NCBI Gene Model | MGI Sequence Detail 76980 C57BL/6J ±  kb
transcript NM_001277867 RefSeq | MGI Sequence Detail 7754 C57BL/6  
polypeptide A6H5Y1 UniProt | EBI | MGI Sequence Detail 1114 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 56
    cDNA 55
    Primer pair 1

    Microarray probesets 11
Other
Accession IDs
less
MGI:1922504, MGI:2141191, MGI:2141219, MGI:3035377
References
more
  • Summaries
    All 48
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 16
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:312811 Modzelewski AJ, et al., A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development. Cell. 2021 Oct 28;184(22):5541-5558.e22
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory