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Taf2 Gene Detail
Summary
  • Symbol
    Taf2
  • Name
    TATA-box binding protein associated factor 2
  • Synonyms
    150kDa, 4732460C16Rik, CIF150, TAF2B, TAFII150
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443028
    NCBI Gene: 319944
  • Gene Overview
    MyGene.info: TAF2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:55015131-55072152 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 21.96 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    287 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443028
protein coding gene Chr15:55015129-55072193 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021851
protein coding gene Chr15:54082545-54141577 (-)
A/J MGP_AJ_G0021811
protein coding gene Chr15:51938556-51995724 (-)
AKR/J MGP_AKRJ_G0021792
protein coding gene Chr15:53408049-53470053 (-)
BALB/cJ MGP_BALBcJ_G0021818
protein coding gene Chr15:52161218-52218100 (-)
C3H/HeJ MGP_C3HHeJ_G0021592
protein coding gene Chr15:53494952-53553969 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022257
protein coding gene Chr15:56188734-56263898 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019794
protein coding gene Chr15:49172665-49230195 (-)
CAST/EiJ MGP_CASTEiJ_G0021109
protein coding gene Chr15:54082783-54144316 (-)
CBA/J MGP_CBAJ_G0021561
protein coding gene Chr15:58171918-58228831 (-)
DBA/2J MGP_DBA2J_G0021685
protein coding gene Chr15:51832750-51889241 (-)
FVB/NJ MGP_FVBNJ_G0021663
protein coding gene Chr15:50953931-51028975 (-)
LP/J MGP_LPJ_G0021755
protein coding gene Chr15:53878778-53940292 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021687
protein coding gene Chr15:63262398-63328478 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022280
protein coding gene Chr15:53756779-53815537 (-)
PWK/PhJ MGP_PWKPhJ_G0020854
protein coding gene Chr15:51903701-51962491 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020691
protein coding gene Chr15:53500336-53562231 (-)
WSB/EiJ MGP_WSBEiJ_G0021164
protein coding gene Chr15:53739244-53815286 (-)



Homology
more
  • Human Ortholog
    TAF2, TATA-box binding protein associated factor 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TAF2, TATA-box binding protein associated factor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CIF150, MRT40, TAF2B, TAFII150
  • Links
    NCBI Gene ID: 6873
    neXtProt AC: NX_Q6P1X5
    UniProt: Q6P1X5

  • Chr Location
    8q24.12; chr8:119730774-119832858 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 31137
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TAF2
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human TAF2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037343 Ensembl Gene Model | MGI Sequence Detail 57022 C57BL/6J ±  kb
transcript ENSMUST00000041733 Ensembl | MGI Sequence Detail 5031 Not Applicable  
polypeptide ENSMUSP00000043733 Ensembl | MGI Sequence Detail 1198 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR016024 Armadillo-type fold
    IPR037813 Transcription initiation factor TFIID subunit 2
Molecular
Reagents
less
  • All nucleic 97
    cDNA 97

    Microarray probesets 2
Other
Accession IDs
less
MGI:2145997
References
more
  • Summaries
    All 44
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 5
    Phenotypes 17
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:245730 Bardot P, et al., The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo. Development. 2017 Oct 15;144(20):3808-3818

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory