Taf2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Taf2
TATA-box binding protein associated factor 2
MGI:2443028

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Taf2^em1Dsar/Taf2^em1Dsar involves: C57BL/6 * DBA	abnormal liver physiology	J:376591
	increased incidence of tumors by chemical induction	J:376591
	increased susceptibility to xenobiotic induced morbidity/mortality	J:376591
	liver fibrosis	J:376591
	liver inflammation	J:376591
Taf2^{tm1b(EUCOMM)Hmgu}/Taf2⁺ C57BL/6N-Taf2^{tm1b(EUCOMM)Hmgu}/Ics	abnormal cholesterol homeostasis	J:211773
	decreased grip strength	J:211773
	hyperactivity	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
	long tibia	J:211773
Taf2^{tm1b(EUCOMM)Hmgu}/Taf2^{tm1b(EUCOMM)Hmgu} C57BL/6N-Taf2^{tm1b(EUCOMM)Hmgu}/Ics	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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