Taf2^em1Dsar
Endonuclease-mediated Allele Detail

Summary

• Symbol: Taf2^em1Dsar
• Name: TATA-box binding protein associated factor 2; endonuclease-mediated mutation 1, Devanand Sarkar
• MGI ID: MGI:8275769
• Gene: Taf2 Location: Chr15:54878527-54935548 bp, - strand Genetic Position: Chr15, 21.96 cM
• Alliance: Taf2^em1Dsar page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/cas9-mediated mutation using 2 single strand repair oligos inserted loxP sites 2.44 kb upstream of exon 1 and 0.44 kb downstream of exon 3. (J:376591)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Taf2 Mutation: 71 strains or lines available

References

• Original: J:376591 Reghupaty SC, et al., TATA-box binding protein-associated factor 2 (TAF2) in hepatocyte survival and tumorigenesis. Hepatology. 2025 May 19
• All: 1 reference(s)