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Adamts19 Gene Detail
Summary
  • Symbol
    Adamts19
  • Name
    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
  • Synonyms
    D230034E10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442875
    NCBI Gene: 240322
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:58836667-59054060 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 33.78 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1505 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442875
 protein coding gene Chr18:58835992-59054060 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024455
 protein coding gene Chr18:58413112-58636075 (+)
A/J MGP_AJ_G0024421
 protein coding gene Chr18:56031678-56245036 (+)
AKR/J MGP_AKRJ_G0024391
 protein coding gene Chr18:57584836-57796983 (+)
BALB/cJ MGP_BALBcJ_G0024421
 protein coding gene Chr18:56192522-56399551 (+)
C3H/HeJ MGP_C3HHeJ_G0024188
 protein coding gene Chr18:57786362-58011969 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024867
 protein coding gene Chr18:60214809-60443413 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022299
 protein coding gene Chr18:55592584-55787307 (+)
CAST/EiJ MGP_CASTEiJ_G0023662
 protein coding gene Chr18:57812862-58030441 (+)
CBA/J MGP_CBAJ_G0024158
 protein coding gene Chr18:62159740-62402608 (+)
DBA/2J MGP_DBA2J_G0024288
 protein coding gene Chr18:55730501-55949769 (+)
FVB/NJ MGP_FVBNJ_G0024255
 protein coding gene Chr18:55107127-55317573 (+)
LP/J MGP_LPJ_G0024373
 protein coding gene Chr18:58329003-58547911 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024285
 protein coding gene Chr18:63677197-63908964 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024914
 protein coding gene Chr18:57697532-57926477 (+)
PWK/PhJ MGP_PWKPhJ_G0023406
 protein coding gene Chr18:55762455-55970745 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023212
 protein coding gene Chr18:57787592-57995060 (+)
WSB/EiJ MGP_WSBEiJ_G0023725
 protein coding gene Chr18:57606368-57824236 (+)



Homology
more
  • Human Ortholog
    ADAMTS19, ADAM metallopeptidase with thrombospondin type 1 motif 19
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ADAMTS19, ADAM metallopeptidase with thrombospondin type 1 motif 19
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 171019
    neXtProt AC: NX_Q8TE59
    UniProt: Q8TE59

  • Chr Location
    5q23.3; chr5:129460281-129738683 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    175
  • Tissues
    52
  • cDNA Data
    19
  • Literature Summary
    13
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053441 Ensembl Gene Model | MGI Sequence Detail 217394 C57BL/6J ±  kb
transcript ENSMUST00000052907 Ensembl | MGI Sequence Detail 5145 Not Applicable  
polypeptide ENSMUSP00000050535 Ensembl | MGI Sequence Detail 1210 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 20
    Primer pair 4

    Microarray probesets 2
Other
Accession IDs
less
MGI:2147293
References
more
  • Summaries
    All 38
    Developmental Gene Expression 13
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:258360 Lin W, et al., Zinc transporter Slc39a8 is essential for cardiac ventricular compaction. J Clin Invest. 2018 Feb 1;128(2):826-833
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/26/2019
MGI 6.14 		The Jackson Laboratory