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Adamts19 Gene Detail
Summary
  • Symbol
    Adamts19
  • Name
    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
  • Synonyms
    D230034E10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442875
    NCBI Gene: 240322
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr18:58836764-59053678 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      216915 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 33.78 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ADAMTS19, ADAM metallopeptidase with thrombospondin type 1 motif 19
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ADAMTS19, ADAM metallopeptidase with thrombospondin type 1 motif 19
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 171019
    neXtProt AC: NX_Q8TE59
    UniProt: Q8TE59

  • Chr Location
    5q23.3; chr5:129460281-129738683 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    175
  • Tissues
    52
  • cDNA Data
    19
  • Literature Summary
    13
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000053441 Ensembl Gene Model | MGI Sequence Detail 216915 C57BL/6J ±  kb
    transcript ENSMUST00000052907 Ensembl | MGI Sequence Detail 4666 Not Applicable  
    polypeptide ENSMUSP00000050535 Ensembl | MGI Sequence Detail 1210 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      1504 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 24
      cDNA 20
      Primer pair 4

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2147293
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 13
      Gene Ontology 2
      Phenotypes 5
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:258360 Lin W, et al., Zinc transporter Slc39a8 is essential for cardiac ventricular compaction. J Clin Invest. 2018 Feb 1;128(2):826-833
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    07/10/2018
    MGI 6.12     		The Jackson Laboratory