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Osbpl2
Gene Detail
Symbol

Name
ID
Osbpl2
oxysterol binding protein-like 2
MGI:2442832
Synonyms
C130070J12Rik, ORP-2
Feature Type
protein coding gene
Genetic Map
Chromosome 2
102.64 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:180119306-180162680 bp, + strand
From VEGA annotation of GRCm38

  43375 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77324  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Osbpl2

Human
homologs
Human Homolog OSBPL2, oxysterol binding protein-like 2
NCBI Gene ID 9885
neXtProt AC  NX_Q9H1P3
Human Synonyms  ORP2, ORP-2
Human Chr (Location)  20q13.33; chr20:62238485-62296213 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(2) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Osbpl2 interacts with 209 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process lipid transport, transport
Component cellular_component
Function cholesterol binding, lipid binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (13)    Tissues (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 13
cDNA source data(73)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(74) cDNA(73) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000016257 (Evidence)
Ensembl Gene ModelENSMUSG00000039050 (Evidence)
Entrez Gene228983 (Evidence)
UniGene253578
DFCITC1576905, TC1673994
DoTSDT.101337614, DT.91407625, DT.485106
NIA Mouse Gene IndexU002951
Consensus CDS ProjectCCDS17170.1
International Mouse Knockout Project StatusOsbpl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016257 VEGA Gene Model | MGI Sequence Detail 43375 C57BL/6J ±  kb
transcript OTTMUST00000038983 VEGA | MGI Sequence Detail 2805 Not Applicable 
polypeptide OTTMUSP00000017424 VEGA | MGI Sequence Detail 484 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(231 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000648 Oxysterol-binding protein
InterPro IPR018494 Oxysterol-binding protein, conserved site
Protein Ontology PR:000012048 oxysterol-binding protein-related protein 2
References
(Earliest) J:78568 Anniss AM, et al., An oxysterol-binding protein family identified in the mouse. DNA Cell Biol. 2002 Aug;21(8):571-80
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory