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Dennd1a Gene Detail
Summary
  • Symbol
    Dennd1a
  • Name
    DENN/MADD domain containing 1A
  • Synonyms
    6030446I19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442794
    NCBI Gene: 227801
  • Gene Overview
    MyGene.info: DENND1A
  • Alliance
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:37798990-38287384 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 24.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1007 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442794
protein coding gene Chr2:37798990-38287390 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025700
protein coding gene Chr2:36518229-37029015 (-)
A/J MGP_AJ_G0025677
protein coding gene Chr2:35024273-35509055 (-)
AKR/J MGP_AKRJ_G0025647
protein coding gene Chr2:36181087-36677680 (-)
BALB/cJ MGP_BALBcJ_G0025672
protein coding gene Chr2:35081790-35561450 (-)
C3H/HeJ MGP_C3HHeJ_G0025433
protein coding gene Chr2:36101772-36598468 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026118
protein coding gene Chr2:37553941-38065863 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023523
protein coding gene Chr2:33688512-34163172 (-)
CAST/EiJ MGP_CASTEiJ_G0024896
protein coding gene Chr2:36025125-36539205 (-)
CBA/J MGP_CBAJ_G0025412
protein coding gene Chr2:38959856-39498366 (-)
DBA/2J MGP_DBA2J_G0025544
protein coding gene Chr2:34766860-35257323 (-)
FVB/NJ MGP_FVBNJ_G0025506
protein coding gene Chr2:34645562-35123650 (-)
LP/J MGP_LPJ_G0025631
protein coding gene Chr2:36410789-36912673 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025537
protein coding gene Chr2:38562905-39115942 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026176
protein coding gene Chr2:36066316-36569382 (-)
PWK/PhJ MGP_PWKPhJ_G0024638
protein coding gene Chr2:34663994-35155130 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024443
protein coding gene Chr2:36185281-36687271 (-)
WSB/EiJ MGP_WSBEiJ_G0024964
protein coding gene Chr2:36247075-36738417 (-)



Homology
more
  • Human Ortholog
    DENND1A, DENN domain containing 1A
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DENND1A, DENN domain containing 1A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FAM31A, KIAA1608
  • Links
    NCBI Gene ID: 57706
    neXtProt AC: NX_Q8TEH3
    UniProt: Q8TEH3

  • Chr Location
    9q33.3; chr9:123379654-123930158 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 227801 NCBI Gene Model | MGI Sequence Detail 488395 C57BL/6J ±  kb
transcript NM_001362973 RefSeq | MGI Sequence Detail 4481 C57BL/6  
polypeptide Q8K382 UniProt | EBI | MGI Sequence Detail 1016 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory