Dennd1a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dennd1a
DENN domain containing 1A
MGI:2442794

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dennd1a^em1(IMPC)Mbp/Dennd1a⁺ C57BL/6N-Dennd1a^em1(IMPC)Mbp/MbpMmucd	abnormal neural tube closure	J:211773
	abnormal neural tube morphology	J:211773
	decreased thigmotaxis	J:211773
Dennd1a^em1(IMPC)Mbp/Dennd1a^em1(IMPC)Mbp C57BL/6N-Dennd1a^em1(IMPC)Mbp/MbpMmucd	abnormal embryo turning	J:211773
	abnormal forebrain development	J:211773
	abnormal heart morphology	J:211773
	abnormal hindbrain development	J:211773
	abnormal neural tube closure	J:211773
	abnormal neural tube morphology	J:211773
	embryonic growth retardation	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Dennd1a^em1Jgfu/Dennd1a^em1Jgfu Not Specified	abnormal cholangiocyte morphology	J:276703
	abnormal embryonic hematopoiesis	J:276703
	abnormal liver development	J:276703
	abnormal primordial germ cell migration	J:276703
	absent heartbeat	J:276703
	decreased apoptosis	J:276703
	decreased cell proliferation	J:276703
	decreased hepatocyte proliferation	J:276703
	embryonic lethality during organogenesis, complete penetrance	J:276703
	enlarged brain ventricles	J:276703
	increased apoptosis	J:276703
	increased brain size	J:276703
	increased forebrain size	J:276703
	increased hindbrain size	J:276703
	increased midbrain size	J:276703
	pale liver	J:276703
	small liver	J:276703

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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