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Cpeb2 Gene Detail
Summary
  • Symbol
    Cpeb2
  • Name
    cytoplasmic polyadenylation element binding protein 2
  • Synonyms
    A630055H10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442640
    NCBI Gene: 231207
Location & Maps
more
  • Sequence Map
    Chr5:43233170-43289724 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      56555 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 23.65 cM, cytoband B
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CPEB2, cytoplasmic polyadenylation element binding protein 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CPEB2, cytoplasmic polyadenylation element binding protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CPEB-2, CPE-BP2, hCPEB-2
  • Links
    NCBI Gene ID: 132864
    neXtProt AC: NX_Q7Z5Q1

  • Chr Location
    4p15.33; chr4:15002451-15070153 (+)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    21 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    4
  • Genomic Mutations
    6 involving Cpeb2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023193 VEGA Gene Model | MGI Sequence Detail 56555 C57BL/6J ±  kb
transcript OTTMUST00000133640 VEGA | MGI Sequence Detail 6846 Not Applicable  
polypeptide OTTMUSP00000071012 VEGA | MGI Sequence Detail 1022 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    223 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR032296 Cytoplasmic polyadenylation element-binding protein, ZZ domain
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR000504 RNA recognition motif domain
Molecular
Reagents
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  • All nucleic 34
    cDNA 33
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 9
    Phenotypes 21
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:181762 Chen PJ, et al., CPEB2-eEF2 interaction impedes HIF-1alpha RNA translation. EMBO J. 2012 Feb 15;31(4):959-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory