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Rnf43
Gene Detail
 Symbol
Name
ID
Rnf43
ring finger protein 43
MGI:2442609
Synonyms 4732452J19Rik
Feature Type protein coding gene
Genetic Map
Chromosome 11
52.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:87662722-87735539 bp, + strand
From VEGA annotation of GRCm38

  72818 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37742  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Rnf43

Human
homologs
Human Homolog RNF43, ring finger protein 43
NCBI Gene ID 54894
neXtProt AC  NX_Q68DV7
Human Synonyms  RNF124, URCC
Human Chr (Location)  17q22; chr17:58353676-58417570 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rnf43 interacts with 191 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process negative regulation of Wnt signaling pathway, protein ubiquitination, ...
Component endoplasmic reticulum, integral component of membrane, ...
Function coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (83)    Tissues (31)    Images (30)
Theiler Stages: 17, 18, 22, 23, 27
Assay TypeResults
RNA in situ 83
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000001292 (Evidence)
Ensembl Gene ModelENSMUSG00000034177 (Evidence)
Entrez Gene207742 (Evidence)
DFCITC1583152, TC1593366, TC1656419, TC1728983
NIA Mouse Gene IndexU013145
EC6.3.2.-
Consensus CDS ProjectCCDS25215.2
International Mouse Knockout Project StatusRnf43
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001292 VEGA Gene Model | MGI Sequence Detail 72818 C57BL/6J ±  kb
transcript OTTMUST00000002595 VEGA | MGI Sequence Detail 4037 Not Applicable 
polypeptide OTTMUSP00000001287 VEGA | MGI Sequence Detail 784 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(6) UniProt(4)
Polymorphisms SNPs within 2kb(216 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000014137 E3 ubiquitin-protein ligase RNF43
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:186765 Koo BK, et al., Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors. Nature. 2012 Aug 30;488(7413):665-9
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory