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Adap1 Gene Detail
Summary
  • Symbol
    Adap1
  • Name
    ArfGAP with dual PH domains 1
  • Synonyms
    4930431P11Rik, Centa1, centaurin alpha 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442201
    NCBI Gene: 231821
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:139271876-139325464 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 78.27 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    310 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442201
protein coding gene Chr5:139271876-139325622 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030279
protein coding gene Chr5:144228765-144293536 (-)
A/J MGP_AJ_G0030248
protein coding gene Chr5:138124600-138179022 (-)
AKR/J MGP_AKRJ_G0030180
protein coding gene Chr5:142430673-142485546 (-)
BALB/cJ MGP_BALBcJ_G0030265
protein coding gene Chr5:139372074-139428048 (-)
C3H/HeJ MGP_C3HHeJ_G0029976
protein coding gene Chr5:143200734-143256095 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030710
protein coding gene Chr5:149551421-149614309 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027928
protein coding gene Chr5:131985097-132039988 (-)
CAST/EiJ MGP_CASTEiJ_G0029381
protein coding gene Chr5:142611060-142669884 (-)
CBA/J MGP_CBAJ_G0029946
protein coding gene Chr5:155718235-155773993 (-)
DBA/2J MGP_DBA2J_G0030096
protein coding gene Chr5:137938598-137992931 (-)
FVB/NJ MGP_FVBNJ_G0030051
protein coding gene Chr5:137040473-137098078 (-)
LP/J MGP_LPJ_G0030182
protein coding gene Chr5:144850214-144906535 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030082
protein coding gene Chr5:158402009-158458844 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030750
protein coding gene Chr5:142237260-142296481 (-)
PWK/PhJ MGP_PWKPhJ_G0029096
protein coding gene Chr5:136932835-136988872 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028932
protein coding gene Chr5:139921593-139982438 (-)
WSB/EiJ MGP_WSBEiJ_G0029455
protein coding gene Chr5:143001974-143063050 (-)



Homology
more
  • Human Ortholog
    ADAP1, ArfGAP with dual PH domains 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ADAP1, ArfGAP with dual PH domains 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CENTA1, GCS1L, p42IP4
  • Links
    NCBI Gene ID: 11033
    neXtProt AC: NX_O75689
    UniProt: O75689

  • Chr Location
    7p22.3; chr7:897900-955407 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 231821 NCBI Gene Model | MGI Sequence Detail 53589 C57BL/6J ±  kb
transcript NM_172723 RefSeq | MGI Sequence Detail 2418 C57BL/6  
polypeptide NP_766311 RefSeq | MGI Sequence Detail 374 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    cDNA 28

    Microarray probesets 4
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory