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Adap1 Gene Detail
Summary
  • Symbol
    Adap1
  • Name
    ArfGAP with dual PH domains 1
  • Synonyms
    4930431P11Rik, Centa1, centaurin alpha 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442201
    NCBI Gene: 231821
Location & Maps
more
  • Sequence Map
    Chr5:139271876-139325622 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      53747 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 78.27 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ADAP1, ArfGAP with dual PH domains 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ADAP1, ArfGAP with dual PH domains 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CENTA1, GCS1L, p42IP4
  • Links
    NCBI Gene ID: 11033
    neXtProt AC: NX_O75689

  • Chr Location
    7p22.3; chr7:897900-955407 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    13
  • Gene trapped
    9
  • Targeted
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025185 VEGA Gene Model | MGI Sequence Detail 53747 C57BL/6J ±  kb
transcript OTTMUST00000062005 VEGA | MGI Sequence Detail 2557 Not Applicable  
polypeptide OTTMUSP00000030520 VEGA | MGI Sequence Detail 374 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    310 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR001164 Arf GTPase activating protein
    IPR011993 PH domain-like
    IPR001849 Pleckstrin homology domain
Molecular
Reagents
less
  • All nucleic 27
    cDNA 27

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory