Adap1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adap1
ArfGAP with dual PH domains 1
MGI:2442201

10 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adap1^tm1.1Ryya/Adap1^tm1.1Ryya involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal dendritic spine morphology	J:308995
	abnormal enzyme/coenzyme activity	J:308995
	abnormal hippocampal pyramidal neuron dendrite morphology	J:308995
	abnormal spatial reference memory	J:308995
	normal behavior/neurological phenotype	J:308995
	enhanced long-term potentiation	J:308995
	increased dendritic spine density	J:308995
	normal nervous system phenotype	J:308995
Adap1^{tm1a(EUCOMM)Wtsi}/Adap1^{tm1a(EUCOMM)Wtsi} C57BL/6N-Adap1^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased memory-marker NK cell number	J:211773
	increased NK cell number	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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