About   Help   FAQ
B3gat2 Gene Detail
Summary
  • Symbol
    B3gat2
  • Name
    beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
  • Synonyms
    GlcAT-S
  • Feature Type
    protein coding gene
  • IDs
    MGI:2389490
    NCBI Gene: 280645
  • Gene Overview
    MyGene.info: B3GAT2
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:23761926-23847865 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 9.75 cM, cytoband A4-B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    688 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2389490
protein coding gene Chr1:23761753-23849158 (.)
129S1/SvImJ MGP_129S1SvImJ_G0015885
protein coding gene Chr1:21573336-21674017 (+)
A/J MGP_AJ_G0015866
protein coding gene Chr1:21162711-21244245 (+)
AKR/J MGP_AKRJ_G0015823
protein coding gene Chr1:21370489-21459317 (+)
BALB/cJ MGP_BALBcJ_G0015822
protein coding gene Chr1:20895293-20982895 (+)
C3H/HeJ MGP_C3HHeJ_G0015656
protein coding gene Chr1:21382747-21465434 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016276
protein coding gene Chr1:22547772-22641185 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0013995
protein coding gene Chr1:19244467-19322615 (+)
CAST/EiJ MGP_CASTEiJ_G0015235
protein coding gene Chr1:21486901-21574798 (+)
CBA/J MGP_CBAJ_G0015628
protein coding gene Chr1:23111945-23187924 (+)
DBA/2J MGP_DBA2J_G0015727
protein coding gene Chr1:20647499-20729702 (+)
FVB/NJ MGP_FVBNJ_G0015731
protein coding gene Chr1:20420363-20499283 (+)
LP/J MGP_LPJ_G0015799
protein coding gene Chr1:21791254-21873058 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015751
protein coding gene Chr1:24113290-24205597 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016323
protein coding gene Chr1:21271604-21355784 (+)
PWK/PhJ MGP_PWKPhJ_G0015018
protein coding gene Chr1:20410267-20497085 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014799
protein coding gene Chr1:21386101-21476662 (+)
WSB/EiJ MGP_WSBEiJ_G0015298
protein coding gene Chr1:21218092-21302066 (+)



Homology
more
  • Human Ortholog
    B3GAT2, beta-1,3-glucuronyltransferase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    B3GAT2, beta-1,3-glucuronyltransferase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GLCATS
  • Links
    NCBI Gene ID: 135152
    neXtProt AC: NX_Q9NPZ5
    UniProt: Q9NPZ5

  • Chr Location
    6q13; chr6:70861366-70957085 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving B3gat2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 280645 NCBI Gene Model | MGI Sequence Detail 85940 C57BL/6J ±  kb
transcript NM_172124 RefSeq | MGI Sequence Detail 4367 Not Specified  
polypeptide P59270 UniProt | EBI | MGI Sequence Detail 324 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 7
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:75411 Yamamoto S, et al., Molecular cloning and genomic analysis of mouse glucuronyltransferase involved in biosynthesis of the HNK-1 epitope. J Biochem. 2002 Mar;131(3):337-47
  • Latest
    J:243894 Yabuno K, et al., A Sulfated Glycosaminoglycan Linkage Region is a Novel Type of Human Natural Killer-1 (HNK-1) Epitope Expressed on Aggrecan in Perineuronal Nets. PLoS One. 2015;10(12):e0144560

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory