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Tmem63b Gene Detail
Summary
  • Symbol
    Tmem63b
  • Name
    transmembrane protein 63b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387609
    NCBI Gene: 224807
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr17:45660171-45686905 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      26735 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 22.59 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TMEM63B, transmembrane protein 63B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TMEM63B, transmembrane protein 63B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C6orf110
  • Links
    NCBI Gene ID: 55362
    neXtProt AC: NX_Q5T3F8
    UniProt: Q5T3F8

  • Chr Location
    6p21.1; chr6:44126628-44155519 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    104
  • Tissues
    16
  • cDNA Data
    111
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000031349 VEGA Gene Model | MGI Sequence Detail 26735 C57BL/6J ±  kb
    transcript OTTMUST00000077661 VEGA | MGI Sequence Detail 3284 Not Applicable  
    polypeptide OTTMUSP00000041124 VEGA | MGI Sequence Detail 832 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      116 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000032717 CSC1-like protein 2
      (term hierarchy)
    • InterPro Domains
      IPR027815 10TM putative phosphate transporter, cytosolic domain
      IPR003864 Calcium-dependent channel, 7TM region, putative phosphate
      IPR032880 Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain
    Molecular
    Reagents
    less
    • All nucleic 111
      cDNA 111

      Microarray probesets 3
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    06/12/2018
    MGI 6.12     		The Jackson Laboratory