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Lzts2
Gene Detail
 Symbol
Name
ID
Lzts2
leucine zipper, putative tumor suppressor 2
MGI:2385095
Synonyms MGC:7094, mKIAA1813
Feature Type protein coding gene
Genetic Map
Chromosome 19
38.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:45015176-45027104 bp, + strand
From NCBI annotation of GRCm38

  11929 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:15690  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Lzts2

Human
homologs
Human Homolog LZTS2, leucine zipper, putative tumor suppressor 2
NCBI Gene ID 84445
neXtProt AC  NX_Q9BRK4
Human Synonyms  LAPSER1
Human Chr (Location)  10q24; chr10:100997107-101007836 (+)  GRCh38
Alleles
and
phenotypes
All alleles(18) : Gene trapped(15) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display defects in urinary tract development.
 
Phenotype Images(3)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process cell cycle, cell division, ...
Component cytoplasm, cytoskeleton, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000035342 (Evidence)
Entrez Gene226154 (Evidence)
NIA Mouse Gene IndexU019497
Consensus CDS ProjectCCDS29855.1
International Mouse Knockout Project StatusLzts2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 226154 NCBI Gene Model | MGI Sequence Detail 11929 C57BL/6J ±  kb
transcript NM_145503 RefSeq | MGI Sequence Detail 2825 C57BL/6 
polypeptide Q91YU6 UniProt | EBI | MGI Sequence Detail 671 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(20 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000031890 leucine zipper putative tumor suppressor 2
Graphical View of Protein Domain Structure
References (Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:196012 Johnson DT, et al., Deletion of leucine zipper tumor suppressor 2 (Lzts2) increases susceptibility to tumor development. J Biol Chem. 2013 Feb 8;288(6):3727-38
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory