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Slc26a7
Gene Detail
 Symbol
Name
ID
Slc26a7
solute carrier family 26, member 7
MGI:2384791
Synonyms MGC:30955
Feature Type protein coding gene
Genetic Map
Chromosome 4
6.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:14502430-14621805 bp, - strand
From VEGA annotation of GRCm38

  119376 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13770  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Slc26a7

Human
homologs
Human Homolog SLC26A7, solute carrier family 26 (anion exchanger), member 7
NCBI Gene ID 115111
neXtProt AC  NX_Q8TE54
Human Synonyms  SUT2
Human Chr (Location)  8q23; chr8:91209494-91398155 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice deficient for this marker have a reduce arterial pH and reduced serum bicarbonate. Urine is more concentrated and has an elevated pH.
 
Interactions
Slc26a7 interacts with 365 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (28 annotations)
Process anion transport, bicarbonate transport, ...
Component basolateral plasma membrane, cytoplasm, ...
Function anion:anion antiporter activity, anion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (336)    Tissues (136)    Images (34)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 336
cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(4) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000004548 (Evidence)
Ensembl Gene ModelENSMUSG00000040569 (Evidence)
Entrez Gene208890 (Evidence)
DFCITC1588752, TC1624250, TC1648706
DoTSDT.101188089, DT.91415553
NIA Mouse Gene IndexU024856
Consensus CDS ProjectCCDS17979.1
International Mouse Knockout Project StatusSlc26a7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004548 VEGA Gene Model | MGI Sequence Detail 119376 C57BL/6J ±  kb
transcript OTTMUST00000010299 VEGA | MGI Sequence Detail 5165 Not Applicable 
polypeptide OTTMUSP00000004887 VEGA | MGI Sequence Detail 656 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(6) UniProt(3)
Polymorphisms SNPs within 2kb(859 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002645 STAS domain
InterPro IPR011547 Sulphate transporter
Protein Ontology PR:000015042 anion exchange transporter
References (Earliest) J:131477 Petrovic S, et al., Identification of a basolateral Cl-/HCO3- exchanger specific to gastric parietal cells. Am J Physiol Gastrointest Liver Physiol. 2003 Jun;284(6):G1093-103
(Latest) J:192414 Dawson PA, et al., Placental, renal, and ileal sulfate transporter gene expression in mouse gestation. Biol Reprod. 2012 Aug;87(2):43
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory