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Slc26a7
Gene Detail
Symbol

Name
ID
Slc26a7
solute carrier family 26, member 7
MGI:2384791
Synonyms
MGC:30955
Feature Type
protein coding gene
Genetic Map
Chromosome 4
6.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:14502430-14621805 bp, - strand
From VEGA annotation of GRCm38

  119376 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13770  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: SLC26A7
Gene Tree: Slc26a7

Human
homologs
SLC26A7, solute carrier family 26 (anion exchanger), member 7
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 115111
neXtProt AC: NX_Q8TE54

Human Synonyms: SUT2

Human Chr (Location): 8q23; chr8:91209494-91398155 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice deficient for this marker have a reduce arterial pH and reduced serum bicarbonate. Urine is more concentrated and has an elevated pH.
 
Interactions
Slc26a7 interacts with 364 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (34 annotations)
Process anion transmembrane transport, anion transport, ...
Component basolateral plasma membrane, cytoplasm, ...
Function anion:anion antiporter activity, anion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (336)    Tissues (136)    Images (34)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 336
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc26a7    NEW 
Molecular
reagents
All nucleic(5) cDNA(4) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000004548 (Evidence)
Ensembl Gene Model ENSMUSG00000040569 (Evidence)
Entrez Gene 208890 (Evidence)
DFCI TC1588752, TC1624250, TC1648706
DoTS DT.101188089, DT.91415553
NIA Mouse Gene Index U024856
Consensus CDS Project CCDS17979.1
International Mouse Phenotyping Consortium Status Slc26a7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004548 VEGA Gene Model | MGI Sequence Detail 119376 C57BL/6J ±  kb
transcript OTTMUST00000010299 VEGA | MGI Sequence Detail 5165 Not Applicable 
polypeptide OTTMUSP00000004887 VEGA | MGI Sequence Detail 656 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(6) UniProt(3)
Polymorphisms
SNPs within 2kb(859 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001902 SLC26A/SulP transporter
InterPro IPR011547 SLC26A/SulP transporter domain
InterPro IPR030329 Solute carrier family 26 member 7
InterPro IPR002645 STAS domain
Protein Ontology PR:000015042 anion exchange transporter
References
(Earliest) J:131477 Petrovic S, et al., Identification of a basolateral Cl-/HCO3- exchanger specific to gastric parietal cells. Am J Physiol Gastrointest Liver Physiol. 2003 Jun;284(6):G1093-103
(Latest) J:216082 Kim KX, et al., Slc26a7 chloride channel activity and localization in mouse Reissner's membrane epithelium. PLoS One. 2014;9(5):e97191
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory