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Nav1 Gene Detail
Summary
  • Symbol
    Nav1
  • Name
    neuron navigator 1
  • Synonyms
    9930003A20Rik, C230080M11Rik, mKIAA1151, POMFIL3, steerin-1, unc53H1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2183683
    NCBI Gene: 215690
  • Gene Overview
    MyGene.info: NAV1
Location & Maps
more
  • Sequence Map
    Chr1:135434580-135607295 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      172716 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 58.79 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    NAV1, neuron navigator 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NAV1, neuron navigator 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    POMFIL3, STEERIN1, UNC53H1
  • Links
    NCBI Gene ID: 89796
    neXtProt AC: NX_Q8NEY1

  • Chr Location
    1q32.1; chr1:201539102-201826974 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 10719
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NAV1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    31
  • Chemically induced (other)
    2
  • Gene trapped
    26
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Nav1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049802 VEGA Gene Model | MGI Sequence Detail 172716 C57BL/6J ±  kb
transcript OTTMUST00000126850 VEGA | MGI Sequence Detail 13117 Not Applicable  
polypeptide OTTMUSP00000068571 VEGA | MGI Sequence Detail 1875 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    3234 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 171
    cDNA 171

    Microarray probesets 6
Other
Accession IDs
less
MGI:2443315, MGI:2444573, MGI:3040671
References
more
  • Summaries
    All 37
    Developmental Gene Expression 7
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:77366 Coy JF, et al., Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. Gene. 2002 May 15;290(1-2):73-94
  • Latest
    J:212272 Wu J, et al., Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):E2851-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory