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Nav1 Gene Detail
Summary
  • Symbol
    Nav1
  • Name
    neuron navigator 1
  • Synonyms
    9930003A20Rik, C230080M11Rik, mKIAA1151, POMFIL3, steerin-1, unc53H1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2183683
    NCBI Gene: 215690
  • Gene Overview
    MyGene.info: NAV1
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:135434580-135607295 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 58.79 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3234 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2183683
protein coding gene Chr1:135434580-135688116 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016525
protein coding gene Chr1:139202574-139380209 (-)
A/J MGP_AJ_G0016508
protein coding gene Chr1:133938831-134112981 (-)
AKR/J MGP_AKRJ_G0016473
protein coding gene Chr1:137916713-138097431 (-)
BALB/cJ MGP_BALBcJ_G0016468
protein coding gene Chr1:134252420-134427355 (-)
C3H/HeJ MGP_C3HHeJ_G0016294
protein coding gene Chr1:138015806-138198369 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016929
protein coding gene Chr1:144226692-144406612 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014640
protein coding gene Chr1:127040306-127216206 (-)
CAST/EiJ MGP_CASTEiJ_G0015874
protein coding gene Chr1:137100113-137284331 (-)
CBA/J MGP_CBAJ_G0016267
protein coding gene Chr1:149222171-149406118 (-)
DBA/2J MGP_DBA2J_G0016373
protein coding gene Chr1:132932475-133106149 (-)
FVB/NJ MGP_FVBNJ_G0016372
protein coding gene Chr1:131572851-131749881 (-)
LP/J MGP_LPJ_G0016444
protein coding gene Chr1:140437327-140614425 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016397
protein coding gene Chr1:154889348-155069196 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016965
protein coding gene Chr1:137683467-137864396 (-)
PWK/PhJ MGP_PWKPhJ_G0015660
protein coding gene Chr1:131961435-132135242 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015447
protein coding gene Chr1:136652682-136837296 (-)
WSB/EiJ MGP_WSBEiJ_G0015937
protein coding gene Chr1:137718316-137896825 (-)



Homology
more
  • Human Ortholog
    NAV1, neuron navigator 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NAV1, neuron navigator 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    POMFIL3, STEERIN1, UNC53H1
  • Links
    NCBI Gene ID: 89796
    neXtProt AC: NX_Q8NEY1
    UniProt: Q8NEY1

  • Chr Location
    1q32.1; chr1:201648322-201826974 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10719
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NAV1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000009418 Ensembl Gene Model | MGI Sequence Detail 172716 C57BL/6J ±  kb
transcript ENSMUST00000067414 Ensembl | MGI Sequence Detail 13117 Not Applicable  
polypeptide ENSMUSP00000067241 Ensembl | MGI Sequence Detail 1875 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 173
    cDNA 173

    Microarray probesets 6
Other
Accession IDs
less
MGI:2443315, MGI:2444573, MGI:3040671
References
more
  • Summaries
    All 45
    Developmental Gene Expression 7
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:228724 van Beuningen SF, et al., TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays. Neuron. 2015 Dec 16;88(6):1208-26

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory