Nav1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nav1
neuron navigator 1
MGI:2183683

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nav1^em1(IMPC)Mbp/Nav1^em1(IMPC)Mbp C57BL/6N-Nav1^em1(IMPC)Mbp/MbpMmucd	abnormal brain morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	decreased brain size	J:211773
	decreased grip strength	J:211773
	decreased heart rate	J:211773
	enlarged spleen	J:211773
	hyperactivity	J:211773
	increased freezing behavior	J:211773
	prolonged RR interval	J:211773
	small kidney	J:211773
Nav1^em1Gpltz/Nav1^em1Gpltz C57BL/6J-Nav1^em1Gpltz	abnormal CNS synaptic transmission	J:355360
	abnormal cocaine self-administration	J:355360
	abnormal excitatory synapse morphology	J:355360
	abnormal inhibitory synapse morphology	J:355360
	abnormal maternal behavior	J:355360
	abnormal nucleus accumbens morphology	J:355360
	abnormal response to novel object	J:355360
	abnormal spatial reference memory	J:355360
	abnormal synapse morphology	J:355360
	decreased anxiety-related response	J:355360
	decreased body size	J:355360
	decreased brain size	J:355360
	decreased hippocampus volume	J:355360
	decreased synapse density	J:355360
	increased food intake	J:355360
	increased miniature excitatory postsynaptic current frequency	J:355360

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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