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Serpina3f
Gene Detail
 Symbol
Name
ID
Serpina3f
serine (or cysteine) peptidase inhibitor, clade A, member 3F
MGI:2182838
Synonyms 2A1, alpha-1 antiproteinasin, antitrypsin
Feature Type protein coding gene
Genetic Map
Chromosome 12
53.65 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:104214544-104221123 bp, + strand
From VEGA annotation of GRCm38

  6580 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:115927  Vertebrate Homology Class
3 mouse; 1 rat

Protein SuperFamily: serpin
Gene Tree: Serpina3f

Alleles
and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component extracellular region, extracellular space
Function peptidase inhibitor activity, serine-type endopeptidase inhibitor activity
External Resources: FuncBase
Expression
cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(7) Genomic(1) cDNA(6)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000027578 (Evidence)
Ensembl Gene ModelENSMUSG00000066363 (Evidence)
Entrez Gene238393 (Evidence)
DFCITC1589880
DoTSDT.101377451, DT.87072894, DT.91583731
Consensus CDS ProjectCCDS26149.1
International Mouse Knockout Project StatusSerpina3f
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027578 VEGA Gene Model | MGI Sequence Detail 6580 C57BL/6J ±  kb
transcript OTTMUST00000068279 VEGA | MGI Sequence Detail 2248 Not Applicable 
polypeptide OTTMUSP00000034478 VEGA | MGI Sequence Detail 445 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(6) UniProt(4)
Polymorphisms SNPs within 2kb(235 from dbSNP Build 137)    SNPs within 2kb including multiple locations(301)
Protein-related
information
ResourceIDDescription
InterPro IPR023795 Protease inhibitor I4, serpin, conserved site
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000015936 serine protease inhibitor A3F
References (Earliest) J:82699 Forsyth S, et al., A review and comparison of the murine alpha(1)-antitrypsin and alpha(1)-antichymotrypsin multigene clusters with the human clade A serpins. Genomics. 2003 Mar;81(3):336-45
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(23)
Other
accession IDs
MGI:2681849

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory