Serpina3f
Gene Detail

Symbol Name ID

Serpina3f serine (or cysteine) peptidase inhibitor, clade A, member 3F MGI:2182838

Synonyms

2A1, alpha-1 antiproteinasin, antitrypsin

Feature Type

protein coding gene

Genetic Map

Chromosome 12

53.65 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr12:104214544-104221123 bp, + strand From VEGA annotation of GRCm38   6580 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:115927  Vertebrate Homology Class
3 mouse; 1 rat

Protein SuperFamily: serpin
Gene Tree: Serpina3f

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	negative regulation of endopeptidase activity, negative regulation of peptidase activity, ...
Component	extracellular region
Function	peptidase inhibitor activity, serine-type endopeptidase inhibitor activity

External Resources: FuncBase

Expression

cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(7) Genomic(1) cDNA(6)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000027578 (Evidence)
Ensembl Gene Model	ENSMUSG00000066363 (Evidence)
Entrez Gene	238393 (Evidence)
DFCI	TC1589880
DoTS	DT.101377451, DT.87072894, DT.91583731
Consensus CDS Project	CCDS26149.1
International Mouse Knockout Project Status	Serpina3f

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027578	VEGA Gene Model | MGI Sequence Detail	6580	C57BL/6J
transcript	OTTMUST00000068279	VEGA | MGI Sequence Detail	2248	Not Applicable
polypeptide	OTTMUSP00000034478	VEGA | MGI Sequence Detail	445	Not Applicable

All sequences(34) RefSeq(6) UniProt(4)

Polymorphisms

SNPs(163 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023795	Protease inhibitor I4, serpin, conserved site
InterPro	IPR023796	Serpin domain
InterPro	IPR000215	Serpin family
Protein Ontology	PR:000015936	serine protease inhibitor A3F

References

(Earliest) J:82699 Forsyth S, et al., A review and comparison of the murine alpha(1)-antitrypsin and alpha(1)-antichymotrypsin multigene clusters with the human clade A serpins. Genomics. 2003 Mar;81(3):336-45
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(22)

Other accession IDs

MGI:2681849